Results 131 to 140 of about 206,427 (382)

A Natural Resource‐Based View of Circular Economy Practices in the Pharmaceutical Industry

Business Strategy and the Environment, EarlyView.
ABSTRACT Pharmaceutical industry is facing escalating environmental sustainability issues including gaseous emissions, waste generation, and excessive consumption of energy and non‐renewable materials. Nevertheless, the adoption of sustainable business models such as the circular economy (CE) is still in its infancy in this sector due to complex ...
Amna Farrukh, Muhammad Sohaib Sajjad
wiley   +1 more source

A clinical and safety review of paracetamol and ibuprofen in children

InflammoPharmacology, 2017
The antipyretic analgesics, paracetamol, and non-steroidal anti-inflammatory agents NSAIDs are one of the most widely used classes of medications in children.
D. Kanabar
semanticscholar   +1 more source

Analisis Kualitatif Parasetamol Pada Sediaan Jamu Serbuk Pegal Linu Yang Beredar Di Purwokerto [PDF]

, 2009
A study concerning the qualitative analysis of paracetamol in traditional herbs powder for relieving stiff and muscle pain circulating in Purwokerto. This study aimed to identify paracetamol in traditional herbs for relieving stiff and muscle pain.
Firdaus, M. I. (Muhammad), Utami, P. I. (Pri)   +1 more
core   +2 more sources

Introducing the Cis‐2,3‐Bis(trifluoromethyl)cyclopropyl Chemotype: Late‐Stage Installation and Stereoelectronic Properties

ChemistryEurope, EarlyView.
The cis‐2,3‐bis(trifluoromethyl)cyclopropyl chemotype is introduced. The steric demand of this motif is intermediate between that of the heptafluoroisopropyl and prefluorotertbutyl groups; yet, it induces significantly less lipophilicity than these due to its facial polarity.
Daniel Gaviña, Zeyu Feng, David Herrero, Martin Simon, Christopher Golz, Manuel Alcarazo   +5 more
wiley   +1 more source

Self-prescription of Paracetamol by Undergraduate Students in BP Koirala Institution of Health Sciences

Journal of Nepal Medical Association, 2016
Introduction: Self-prescription of medicines are common especially in low income countries. Paracetamol is a common medicine that is self-prescribed also among university students.
Ajay Kumar Yadav, Bijendra Kumar Rai, Shyam Sundar Budhathoki, Anup Ghimire, Shree Ram Shrestha, Gyanendra Bahadur Malla   +5 more
doaj  

Comparison of First Analgesic Demand after Major Surgeries of Obstetrics and Gynecology between Pre-Emptive Versus Intra-Operative Groups by Using Intravenous Paracetamol: A Cross-Sectional Study

, 2022
Humaira Tahir, Pari Gul Baloch, Mubushra Samina, Ifat Balouch, Sundas Ahmad, Zakia Bano   +5 more
openalex   +1 more source

Are some people at increased risk of paracetamol-induced liver injury? A critical review of the literature

European Journal of Clinical Pharmacology, 2017
Paracetamol is one of the world’s most commonly used drugs. In overdose, it is well established to be hepatotoxic. The aim of this review was to identify factors that have been, or actually are, associated with the development of liver injury after ...
T. M. Caparrotta, D. Antoine, J. Dear
semanticscholar   +1 more source

Effects of High‐ and Low‐Fat Meals on the Bioavailability and Pharmacokinetics of Votoplam, a HTT Gene Splicing Modifier

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee, Amy‐Lee Richards, Nageswara Reddy, Brian Beers, Lee Golden, Ronald Kong   +5 more
wiley   +1 more source

A Phase 1, Randomized, Placebo‐Controlled, Multiple‐Dose, Double‐Blind Study to Evaluate and Compare the Pharmacokinetics and Safety of Rimegepant in Healthy Adult Japanese and Caucasian Individuals

Clinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1, randomized, placebo‐controlled, double‐blind study assessed the pharmacokinetic profile of rimegepant (25, 75, or 150 mg once daily for 14 days) in healthy Japanese and Caucasian adults. Exposures were modestly increased in Japanese participants compared with Caucasian participants following a single dose of rimegepant (Day 1 ...
Rajinder Bhardwaj, Chay Ngee Lim, Yinhua Li, Kyle T. Matschke, Richard Bertz, Robert Croop, Jing Liu   +6 more
wiley   +1 more source

Influence of fruit drinks with or without lactobacillus Lp299v on the gastrointestinal uptake of paracetamol in man

BMC Research Notes, 2009
Background Clinical observations have revealed that patients throw up undigested paracetamol tablets several hours following intake of rosehip drink with Lp299v (Proviva).
Edvinsson Lars, Åkerman Ulrika
doaj   +1 more source