Results 51 to 60 of about 9,164 (166)

Paraoxonase and Arylesterase Activities in Patients with Preeclampsia

Eurasian Journal of Medicine, 2019
Objective: Paraoxonase is a high density lipoprotein-associated antioxidant enzyme. The aim of this study was to investigate the serum paraoxonase and arylesterase activities and associations between these enzymes and lipid hydroperoxide (LOOH) in ...
Ayse Nur Aksoy, Nurinnisa Ozturk, Hulya Aksoy, Fatih Akcay   +3 more
doaj  

Repurposing of substances with lactone moiety for the treatment of γ-Hydroxybutyric acid and γ-Butyrolactone intoxication through modulating paraoxonase and PPARγ

Frontiers in Pharmacology, 2022
GHB and GBL are highly accessible recreational drugs of abuse with a high risk of adverse effects and mortality while no specific antidotes exist. These components can also be found in the clinical setting, beverages, and cosmetic products, leading to ...
Sepand Tehrani Fateh, Amir Salehi-Najafabadi   +1 more
doaj   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Health Effects of Bee Products: A Comprehensive Review

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Nutritional composition of bee products and some health effects. ABSTRACT Honey, bee pollen, propolis, bee bread, royal jelly, bee venom, beeswax, and apilarnil are among the bee‐derived products that may serve health‐related purposes, as they exhibit various biological activities such as antibacterial, antiviral, antifungal, antioxidant, anti ...
Nevin Sanlier, Elif Yildiz Kaya, Ikbal Irem Yucel   +2 more
wiley   +1 more source

Novel Enzymes for Biologics with Hydrolytic Activity Against Thiolactones: Computational, Catalytic and Antimicrobial Study

Biologics
Background: Various thiolactones are known as biologically active compounds, capable of stimulating the development of several human diseases and quorum sensing of Gram–positive bacteria.
Maksim Domnin, Anastasia Sarapina, Aysel Aslanli, Olga Senko, Elena Efremenko   +4 more
doaj   +1 more source

Distribution of Paraoxonase 1 polymorphisms and activities in obese patients

Romanian Journal of Laboratory Medicine, 2013
Obiectivul studiului a fost de investigarea fenotipului şi genotipului PON1 la pacienţii români cu obezitate abdominală. Material şi metodă. Loturile din studiu au constat din 88 de pacienţi cu obezitate abdominală şi 46 subiecţi cu circumferinţă ...
Ciumărnean Lorena, Vesa Ştefan C., Dronca Eleonora, Sâmpelean Dorel P., Vlad Vasile C., Moldovan Maria S., Achimaş Cadariu A.   +6 more
doaj   +1 more source

Pulsed Electromagnetic Field Therapy for Mild‐to‐Moderate Knee Osteoarthritis: A Double‐Blind, Randomized, Placebo‐Controlled Clinical Trial

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Current treatments for knee osteoarthritis (OA) offer limited functional and structural improvements. Compared to age‐ and gender‐matched controls, patients with knee OA show a higher prevalence of muscle weakness, which negatively affects their ability to exercise—a key factor in enhancing physical mobility and delaying disease ...
Kenney Ki Lee Lau, Abbey Ssu Chi Chen, Christine Hoi Yan Fu, Jonathan Patrick Ng, Michael Tim Yun Ong, Patrick Shu Hang Yung, Pauline Po Yee Lui   +6 more
wiley   +1 more source

HDL structure and function is profoundly affected when stored frozen in the absence of cryoprotectants

Journal of Lipid Research, 2017
Analysis of structural and functional parameters of HDL has gained significant momentum in recent years because they are stronger predictors of cardiovascular risk than HDL-cholesterol levels. Surprisingly, in most HDL studies, very low attention is paid
Michael Holzer, Sabine Kern, Markus Trieb, Athina Trakaki, Gunther Marsche   +4 more
doaj   +1 more source

Differential Proteomics of Large Extracellular Vesicles in Ovarian Cancer

PROTEOMICS, Volume 26, Issue 2-3, Page 95-104, February 2026.
ABSTRACT Diverse extracellular vesicles (EVs) are present in all body fluids; however, knowledge of large EVs (lEVs) remains limited. Molecular EV profiles vary depending on EV size and the physiological circulatory system, even within the same patient. In this study, we aimed to characterize the proteomic profile of IEVs in ovarian cancer patients and
Kazuhiro Suzuki, Yusuke Yamamoto, Masami Kitagawa, Eri Asano‐Inami, Kosuke Yoshida, Hiroaki Kajiyama, Akira Yokoi   +6 more
wiley   +1 more source

Effect of four weeks of endurance training on serum level of paraoxonase-1 and lipid profile in non-athlete obese men

مجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1.
Amouzad Mahdirejei T, Berarei AR, Farzanegei P, Ahmadi M   +3 more
doaj