Results 61 to 70 of about 361,612 (191)

Cardiovascular Role of Parvocellular Neurons in the Paraventricular Nucleus of the Hypothalamus

, 1996
The paraventricular nucleus of the hypothalamus contains magnocellular and parvocellular neurons. Some parvocellular neurons project to the spinal cord and are likely to directly influence the sympathetic preganglionic motoneurons.
E Badoer
core   +1 more source

Functional identification of central afferent projections conveying information of acute "stress" to the hypothalamic paraventricular nucleus

, 1995
c-fos, corticotropin-releasing factor, neurosecretory neurons, paraventricular nucleus, transcription factors, neuroendocrinology, cholera toxin subunit B, retrograde ...
Mikkelsen, J.D., Larsen, P.J.
core   +1 more source

Dietary melatonin and its benefits on cardiovascular disease

British Journal of Pharmacology, EarlyView.
Cardiovascular disease remains the leading cause of mortality globally, with a disproportionate burden in low‐ and middle‐income countries. Melatonin, a hormone primarily produced by the pineal gland, exhibits notable antioxidant, anti‐inflammatory and immunomodulatory properties that may confer cardiovascular benefits.
Karabo Tisane, Carmelita Abrahams, Sandrine Lecour   +2 more
wiley   +1 more source

Da-Chuan-Xiong Decoction Ameliorates Sodium Sensitivity and Plasma Norepinephrine via Attenuation of Brain Oxidative Stress in the DOCA-Salt Hypertensive Rats

International Journal of Hypertension
Background. Da-Chuan-Xiong Decoction (DCXD) is an aqueous extract from a classic Chinese herbal formula composed of dried rhizomes of Ligusticum chuanxiong Hort and Gastrodia elata Bl. in the mass ratio of 4 : 1.
Qi Zhang, Hao Li, Shan Zhao, Fangfang Li, Yingying Tan   +4 more
doaj   +1 more source

Expression of vasopressin mRNA in the hypothalamus of individuals with a diagnosis of schizophrenia

Brain and Behavior, 2019
Objective This study investigates the expression of mRNA encoding vasopressin in the hypothalamus of autopsy brains of individuals diagnosed with schizophrenia.
Johannes R. Busch, Christina Jacobsen, Niels Lynnerup, Jytte Banner, Morten Møller   +4 more
doaj   +1 more source

Reactive oxygen species in the paraventricular nucleus of the hypothalamus alter sympathetic activity during metabolic syndrome.

Frontiers in Physiology, 2015
The paraventricular nucleus of the hypothalamus (PVN) contains heterogeneous populations of neurons involved in autonomic and neuroendocrine regulation.
JOSIANE CAMPOS CRUZ, Atalia Ferreira Lima Flôr, Maria Socorro França-Silva, Camille M Balarini, Valdir Andrade Braga   +4 more
doaj   +1 more source

Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu, Julia Y. H. Liu, Yasuhiro Nakagami, Zitong Li, Xiaofei Huang, Man P. Ngan, Dexuan Cui, John A. Rudd   +7 more
wiley   +1 more source

Immunoreactivity and distribution of Fos in the mouse brain following diverse general anesthetics

Scientific Reports
General anesthesia induces a range of effects, including unconsciousness, analgesia, amnesia, and immobility. Despite its widespread use for over a century, the underlying mechanisms remain incompletely understood.
Yiwen Hu, Jing Yang, Jing Huang, Zonghong Long, Yu Li, Min Zhang, Zhuoxi Wu, Tingting Yi, Hong Li   +8 more
doaj   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Involvement of the ipsilateral-to-the-pain anterior–superior hypothalamic subunit in chronic cluster headache

The Journal of Headache and Pain
Background Despite hypothalamus has long being considered to be involved in the pathophysiology of cluster headache, the inconsistencies of previous neuroimaging studies and a limited understanding of the hypothalamic areas involved, impede a ...
Stefania Ferraro, Anna Nigri, Maria Grazia Bruzzone, Jean Paul Medina Carrion, Davide Fedeli, Greta Demichelis, Luisa Chiapparini, Giuseppe Ciullo, Ariosky Areces Gonzalez, Alberto Proietti Cecchini, Luca Giani, Benjamin Becker, Massimo Leone   +12 more
doaj   +1 more source