Results 71 to 80 of about 361,612 (191)

Orofacial pain disorder or trigeminal autonomic cephalalgia? Insights into pathophysiology and implications in medicine and dentistry

Headache: The Journal of Head and Face Pain, EarlyView.
There are some headache disorders known as trigeminal autonomic cephalalgias (TACs). When these “headaches” are localized in the mid‐face region, they are known as “trigeminal autonomic orofacial pains” (TAOPs), and they can mimic other types of face pains including dental pain, which puts the patient at risk of receiving treatments that are incorrect.
Marcela Romero‐Reyes, Simon Akerman
wiley   +1 more source

Synaptic output from suprachiasmatic nucleus cholecystokinin neurons regulates locomotor rhythmicity

Frontiers in Neuroscience
BackgroundThe mammalian suprachiasmatic nucleus (SCN) serves as the master circadian pacemaker, which coordinates daily behavioral and physiological rhythms through functionally diverse neuronal subtypes. Cholecystokinin (CCK) is expressed in a subset of
Wanli Chen, Wanli Chen, Wanli Chen, Wanli Chen, Zhixiong Ma, Zhixiong Ma, Zhixiong Ma, Xiaoqing Hao, Xiaoqing Hao, Xiaoqing Hao, Shikang Guan, Shikang Guan, Shikang Guan, Xin Diao, Xin Diao, Xin Diao, Yuehong Huang, Yuehong Huang, Yuehong Huang, Yuehong Huang, Ruogu Liu, Ruogu Liu, Ruogu Liu, Ruogu Liu, Zhengran Li, Zhengran Li, Zhengran Li, Zhengran Li, Bingbing Xue, Bingbing Xue, Bingbing Xue, Tongfei A. Wang, Tongfei A. Wang, Tongfei A. Wang, Tongfei A. Wang   +34 more
doaj   +1 more source

An enhanced expression of hypothalamic neuronal nitric oxide synthase in a rat model of simulated transport stress

BMC Veterinary Research, 2019
Background Transport stress not only causes physiological changes but also induces behavioral responses, including anxiety-like and depression-like behavioral responses in animals.
Jia Wang, Jiao Li, Mingyuan Yu, Yuying Wang, Yunfei Ma   +4 more
doaj   +1 more source

BMAL1 in Anterior Cingulate Cortex Pyramidal Neurons Relieves Pulpitis‐Induced Nocturnal Pain

International Endodontic Journal, EarlyView.
ABSTRACT Aim Nocturnal exacerbation of pulpitis‐induced pain severely disrupts patients' sleep and quality of life, increasing emergency dental care burden. However, the exact mechanisms underlying nocturnal pain remain poorly understood, limiting the development of targeted analgesic strategies.
Yuting Bai, Jialin Si, Jing Zhang, Zhuo Yu, Meng Nian, Yundi Qiao, Xiaoke Wu, Jing Huang, Li‐an Wu   +8 more
wiley   +1 more source

Sex-specific differences in cardiovascular and metabolic hormones with integrated signalling in the paraventricular nucleus of the hypothalamus

, 2017
Many traditional cardiovascular hormones have been implicated in metabolic function. Conversely, many hormones traditionally involved in metabolic regulation have an effect on cardiovascular function. Many of these signalling molecules exert such effects
Paterson, Alex, Murphy, David, Su Yi Loh, Mark F. Rogers, David Murphy, Alex R. Paterson, Alastair V. Ferguson, Charles C. T. Hindmarch, Spencer P. Loewen   +8 more
core   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Microbiome and Metabolomics in Obesity: Advances in Understanding and Interventions Across the Lifespan

Obesity Reviews, EarlyView.
ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati, David Krongauz, Alice Bosco, Antonio Noto, Cristina Piras, Maria Kafyra, Angelica Dessì, Matteo Mauri, Luigi Atzori, Adina Weinberger, Vassilios Fanos, George V. Dedoussis, on behalf of the BETTER4U consortium   +12 more
wiley   +1 more source

Chronic unpredictable stress and long-term ovariectomy affect arginine-vasopressin expression in the paraventricular nucleus of adult female mice

, 2014
Arginine-Vasopressin (AVP) may regulate the hypothalamic-pituitary-adrenal axis (HPA) and its effects on depressive responses. In a recent study, we demonstrated that Chronic Unpredictable Stress (CUS) depressive effects are enhanced by long-term ...
Garcia Segura, Luis, Calmarza-Font, Isabel, Lagunas, N., Lagunas García, Luisa Natalia, Grassi, Daniela, Panzica, G. C., Panzica, GianCarlo, Garcia-Segura, L. M., Diz-Chaves, Yolanda   +8 more
core   +1 more source

Whole-Brain Monosynaptic Afferent Projections to the Cholecystokinin Neurons of the Suprachiasmatic Nucleus

Frontiers in Neuroscience, 2018
The suprachiasmatic nucleus (SCN) is the principal pacemaker driving the circadian rhythms of physiological behaviors. The SCN consists of distinct neurons expressing neuropeptides, including arginine vasopressin (AVP), vasoactive intestinal polypeptide (
Xiang-Shan Yuan, Hao-Hua Wei, Wei Xu, Lu Wang, Wei-Min Qu, Rui-Xi Li, Zhi-Li Huang   +6 more
doaj   +1 more source

Ovariectomy, but not moderate intermittent hypoxia, promotes respiratory instability and risk of obesity in adult female rats

Experimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is a prevalent and complex respiratory disorder associated with recurrent interruptions of air flow during sleep. SA causes sleep fragmentation and intermittent hypoxia which leads to numerous negative health consequences.
Marianne Gagnon, Stéphanie Fournier, François Marcouiller, Natalie J. Michael, Vincent Joseph, Richard Kinkead   +5 more
wiley   +1 more source