Results 21 to 30 of about 12,704 (204)

A Non-Reference Temperature Histogram Method for Determining T_c from Ground-Based Thermal Imagery of Orchard Tree Canopies

Remote Sensing, 2019
Obtaining average canopy temperature (Tc) by thresholding canopy pixels from on-ground thermal imagery has historically been undertaken using ‘wet’ and ‘dry’ reference surfaces in the field (reference temperature thresholding ...
Arachchige Surantha Ashan Salgadoe, Andrew James Robson, David William Lamb, Derek Schneider   +3 more
doaj   +1 more source

Inhibition of Poly ADP-Ribose Glycohydrolase Sensitizes Ovarian Cancer Cells to Poly ADP-Ribose Polymerase Inhibitors and Platinum Agents

Frontiers in Oncology, 2021
BackgroundPoly ADP-ribose glycohydrolase (PARG) is responsible for the catabolism of PARP-synthesized PAR to free ADP-ribose. Inhibition of PARG leads to DNA repair interruption and consequently induces cell death.
Emad Matanes, Emad Matanes, Vanessa M. López-Ozuna, David Octeau, Tahira Baloch, Florentin Racovitan, Amandeep Kaur Dhillon, Roy Kessous, Roy Kessous, Oded Raban, Oded Raban, Liron Kogan, Liron Kogan, Shannon Salvador, Shannon Salvador, Susie Lau, Susie Lau, Walter H. Gotlieb, Walter H. Gotlieb, Amber Yasmeen   +19 more
doaj   +1 more source

Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, HA100, affects oral infectivity in vivo but not virus replication in vitro [PDF]

, 2011
ORF100 (ha100) of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been reported as one of the unique genes of group II alphabaculoviruses encoding a protein located in the occlusion-derived virus (ODV) envelope and nucleocapsid.
Deng, F., Hu, Z., Luo, S., Vlak, J.M., Wang, H., Westenberg, M., Xu, X., Zhang, Y.   +7 more
core   +3 more sources

Good reduction of algebraic groups and flag varieties [PDF]

, 2015
In 1983, Faltings proved that there are only finitely many abelian varieties over a number field of fixed dimension and with good reduction outside a given set of places.
Javanpeykar, Ariyan, Loughran, Daniel
core   +2 more sources

Poly(ADP-ribosyl)ation is involved in the epigenetic control of TET1 gene transcription [PDF]

, 2014
TET enzymes are the epigenetic factors involved in the formation of the Sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis.
Bacalini, MARIA GIULIA, Caiafa, Paola, Calabrese, Roberta, Ciccarone, Fabio, Franceschi, C, Guastafierro, Tiziana, Mariano, Germano, Reale, Anna, Valentini, Elisabetta, Zampieri, Michele   +9 more
core   +9 more sources

PARP and PARG inhibitors in cancer treatment [PDF]

Genes & Development, 2020
Oxidative and replication stress underlie genomic instability of cancer cells. Amplifying genomic instability through radiotherapy and chemotherapy has been a powerful but nonselective means of killing cancer cells. Precision medicine has revolutionized cancer therapy by putting forth the concept of selective targeting of cancer cells. Poly(ADP-ribose)
openaire   +2 more sources

O-GlcNAc has crosstalk with ADP-ribosylation via PARG

Journal of Biological Chemistry, 2023
O-linked N-acetylglucosamine (O-GlcNAc) glycosylation, a prevalent protein post-translational modification (PTM) that occurs intracellularly, has been shown to crosstalk with phosphorylation and ubiquitination. However, it is unclear whether it interplays with other PTMs. Here we studied its relationship with ADP-ribosylation, which involves decorating
Jie Li, Xiangxiang Liu, Bin Peng, Tingting Feng, Wen Zhou, Li Meng, Shanshan Zhao, Xiyuan Zheng, Chen Wu, Shian Wu, Xing Chen, Xingzhi Xu, Jianwei Sun, Jing Li   +13 more
openaire   +2 more sources

PARG suppresses tumorigenesis and downregulates genes controlling angiogenesis, inflammatory response, and immune cell recruitment

BMC Cancer, 2022
Chemokines are highly expressed in tumor microenvironment and play a critical role in all aspects of tumorigenesis, including the recruitment of tumor-promoting immune cells, activation of cancer-associated fibroblasts, angiogenesis, metastasis, and ...
Sarah Johnson, Yaroslava Karpova, Danping Guo, Atreyi Ghatak, Dmitriy A. Markov, Alexei V. Tulin   +5 more
doaj   +1 more source

Antibody RING-Mediated Destruction of Endogenous Proteins [PDF]

, 2020
International ...
Abidi, Naima, Dickerson, David, Hay, Ronald T., Ibrahim, Adel F. M., Prescott, Alan R., Shen, Linnan, Tatham, Michael H., Xirodimas, Dimitris P.   +7 more
core   +4 more sources

Radiation-induced mitotic catastrophe in PARG-deficient cells [PDF]

Journal of Cell Science, 2009
Poly(ADP-ribosyl)ation is a post-translational modification of proteins involved in the regulation of chromatin structure, DNA metabolism, cell division and cell death. Through the hydrolysis of poly(ADP-ribose) (PAR), Poly(ADP-ribose) glycohydrolase (PARG) has a crucial role in the control of life-and-death balance following DNA insult.
Amé, Jean-Christophe, Fouquerel, Elise, Gauthier, Laurent R, Biard, Denis, Boussin, François D, Dantzer, Françoise, Murcia, Gilbert, Schreiber, Valérie   +7 more
openaire   +3 more sources