Results 41 to 50 of about 5,177 (98)

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

Replication-associated base excision repair/single-strand break repair regulates PARG inhibitor response via the PRMT1/PRMT5/ATR axis. [PDF]

NAR Cancer
Ibrahim M, Roos WP, Schwartz JC, Khan MM, Al-Rahahleh RQ, Beers LA, Pearson CR, Langham KT, Boyang L, Clark J, Hayat F, Fang Q, Koczor CA, Migaud ME, Sobol RW.   +14 more
europepmc   +1 more source

Intrinsic PARG inhibitor sensitivity is mimicked by TIMELESS haploinsufficiency and rescued by nucleoside supplementation. [PDF]

NAR Cancer
Coulson-Gilmer C, Littler S, Barnes BM, Brady RM, Anagho HA, Pillay N, Dey M, Macmorland W, Bronder D, Nelson L, Tighe A, Lin WH, Morgan RD, Unwin RD, Nielsen ML, McGrail JC, Taylor SS.   +16 more
europepmc   +1 more source

Homogeneous Time-Resolved Fluorescence-Based Assay to Screen ADP-Ribosyl Hydrolase Inhibitors. [PDF]

Bio Protoc
Yu A, Wu D.
europepmc   +1 more source

PARG Governs a PARylation-Ubiquitination Toggle that Stabilizes RAD51AP1 to Drive Homologous Recombination-Mediated Chemoresistance. [PDF]

Cancer Res
He H, Hu Y, Lu Y, Deng M, Bao Q, Zu D, Zhong Y, Zhang C, You C, Du X, Liu S, He Y, Liu M, Gao L, Gao X, Liu H, Huang Y, Chen Y, Rong D, Tainer JA, Jing J, Shi Y, Shen HM, Ye Z, Cheng X.   +24 more
europepmc   +1 more source

FET proteins and PARylation-dependent condensates promote replication fork reversal and genome stability. [PDF]

Nat Commun
Giansanti C, Schultz JC, Jackson J, Vindigni A, Cortez D.   +4 more
europepmc   +1 more source

Overcoming Resistance to PARP Inhibitors in BRCA-Mutated Cancers: Mechanisms and Therapeutic Strategies. [PDF]

J Cancer
Guo J, Wang Y, Li J, Jiang Z.
europepmc   +1 more source

PARG inhibition in ATM-deficient prostate cancer: from mechanistic discovery to therapeutic potential. [PDF]

J Transl Med
Zhou X, Guo C, Fan Z, Lou Y, Yue Z, Xu W, Xin Z, Ren S.   +7 more
europepmc   +1 more source

Delaying Stress Granule Disassembly by PARG Inhibition Attenuates Renal Tubular Cell Pyroptosis in Acute Kidney Injury. [PDF]

Int J Mol Sci
Song Y, Jiang S, Yang M, Zhu J, Hu B, Su H.   +5 more
europepmc   +1 more source

CHD1L maintains genome integrity by facilitating okazaki fragment maturation. [PDF]

Nucleic Acids Res
Nie L, Fu J, Huang M, Zhang H, Ma T, Yang C, Li S, Wang C, Chen J.   +8 more
europepmc   +1 more source