Results 101 to 110 of about 44,057 (302)

The ubiquitin ligase parkin modulates the execution of autophagy [PDF]

, 2011
Alexander M. Herman, Charbel Moussa
openalex   +1 more source

Trends in the incidence of cancers of the breast and female genital tract in Harare, Zimbabwe 1990–2019

International Journal of Cancer, EarlyView.
What's New? Cancers of the breast and female genital tract represent more than half of all cancers in women in sub‐Saharan Africa. Here, the authors assessed incidence trends in a female population living in urban sub‐Saharan Africa based on the Zimbabwe National Cancer Registry in Harare over a 30‐year period.
Eric Chokunonga, Zvavahera Michael Chirenje, Margaret Borok, Rudo Makunike‐Mutasa, Ntokozo Ndlovu, Justice Mudavanhu, Biying Liu, D. Maxwell Parkin   +7 more
wiley   +1 more source

Supp. Figure 5 from Parkin Deficiency Suppresses Antigen Presentation to Promote Tumor Immune Evasion and Immunotherapy Resistance

, 2023
Renzo Perales‐Linares, Nektaria Maria Leli, Hesham Mohei, Silvia Beghi, Osvaldo D. Rivera, Νεκτάριος Κωστόπουλος, Andrea Giglio, Subin S. George, Mireia Uribe‐Herranz, Francesca Costabile, Stefano Pierini, Sergei Pustylnikov, Giorgos Skoufos, Yoseph Barash, Artemis G. Hatzigeorgiou, Constantinos Koumenis, Amit Maity, Michael T. Lotze, Andrea Facciabene   +18 more
openalex   +1 more source

An Investigation of the Relationship Between Central Bank Unconventional Monetary Policy and Bitcoin Activity

International Journal of Finance &Economics, EarlyView.
ABSTRACT This article investigates whether the unconventional monetary policy (UMP) measures pursued by the Federal Reserve, the Bank of England, the Bank of Japan, and the European Central Bank since the Global Financial Crisis (GFC) are associated with an appetite for cryptocurrency.
Niamh Wylie, Martha O'Hagan‐Luff
wiley   +1 more source

Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation

Nature Communications, 2017
Parkin and PINK1 are involved in damaged mitochondria clearance; however the sequence of events of Parkin activation is not clear. Here, the authors show that binding to phospho-ubiquitin on mitochondria enables Parkin phosphorylation, which allows ...
Matthew Y. Tang, Marta Vranas, Andrea I. Krahn, Shayal Pundlik, Jean- François Trempe, Edward A. Fon   +5 more
doaj   +1 more source

Alpha‐Synuclein Promotes Anterograde Vesicle Transport in Melanocytes and Melanoma Cells: A Pro‐Survival Function

Journal of the Chinese Chemical Society, EarlyView.
Model for how α‐syn modulates the positioning of endolysosomes in melanoma cells. (a) α‐syn tethers endolysosomes to the plasma membrane, a last step in anterograde transport. (b) Loss of α‐syn expression causes the loss of the tethering function, which leads to perinuclear vesicle clustering. Reproduced from the open access article.
Stephan N. Witt
wiley   +1 more source

Superoxide dismutating molecules rescue the toxic effects of PINK1 and parkin loss [PDF]

, 2018
Alice Biosa, Álvaro Sánchez-Martínez, Roberta Filograna, Ana Terriente-Félix, Sarah M. Alam, Mariano Beltramini, Luigi Bubacco, Marco Bisaglia, Alexander J. Whitworth   +8 more
openalex   +1 more source

A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets [PDF]

, 2020
Masashi Watanabe, Yasushi Saeki, Hidehisa Takahashi, Fumiaki Ohtake, Yukiko Yoshida, Yusuke Kasuga, Takeshi Kondo, Hiroaki Yaguchi, Masanobu Suzuki, Hiroki Ishida, Keiji Tanaka, Shigetsugu Hatakeyama   +11 more
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Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites [PDF]

, 2021
Jacqueline M. Tokarew, Daniel N. El-Kodsi, Nathalie A. Lengacher, Travis K. Fehr, Angela Nguyen, Bojan Shutinoski, Brian O’Nuallain, Ming Jin, Jasmine M. Khan, Andy Cheuk‐Him Ng, Juan Li, Qiubo Jiang, Mei Zhang, Liqun Wang, Rajib Sengupta, Kathryn R. Barber, An Tran, Doo Soon Im, Steve Callaghan, David S. Park, Stéphanie Zandee, Xiajun Dong, Clemens R. Scherzer, Alexandre Prat, Eve C. Tsai, Masashi Takanashi, Nobutaka Hattori, Jennifer A. Chan, Luigi Zecca, Andrew B. West, Arne Holmgren, Lawrence G. Puente, Gary S. Shaw, Gergely Tóth, John Woulfe, Peggy Taylor, Julianna J. Tomlinson, Michael G. Schlossmacher   +37 more
openalex   +1 more source

Renal ultrasound after first febrile urinary tract infection in hospitalized children: The ROUTINE prospective observational study protocol

Journal of Hospital Medicine, EarlyView.
Abstract Background Urinary tract infection (UTI) is a common reason for hospitalization in young children. American and Canadian guidelines recommend universal renal ultrasound after a first febrile UTI to identify genitourinary abnormalities that require further management, despite limited supporting evidence. The Renal ultrasOund after first febrile
Sanjay Mahant, Keenjal Mistry, Ann Bayliss, Nicholas Barrowman, Karen Born, Cornelia Borkhoff, Raman Chawla, David D'Arienzo, Aurelie D'Hondt, Kim De Castris‐Garcia, Joana Dos Santos, Olivier Drouin, Ricardo Faingold, Vince Albert Flores, Jessica Foulds, Jeremy Friedman, Lucy Giglia, Joanna Holland, Radha Jetty, Kristopher Kang, Patricia Li, Grace Leo, Armando Lorenzo, Elise Lu, Colin Macarthur, Kyle Millar, Myla E. Moretti, Nassr Nama, Olivia Ostrow, Rachel Pearl, Patricia Parkin, Mandy Rickard, Mahmoud Sakran, Anupam Sehgal, Nader Shaikh, Sepideh Taheri, Otto G. Vanderkooi, Gemma Vomiero, Kim Zhou, Peter J. Gill, the Canadian Paediatric Inpatient Research Network (PIRN)   +40 more
wiley   +1 more source