Results 121 to 130 of about 226,005 (247)

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

UBE4B Mediates Mitophagy via NIPSNAP1 Ubiquitination and NDP52 Recruitment. [PDF]

Int J Mol Sci
Jin B, Qu J, Xu K, Zhang Y, Xu P, Wang X, Zhao B, Jiao X.   +7 more
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

The conserved outer mitochondrial membrane protein Mtch regulates mitophagy during Drosophila intestinal development. [PDF]

PLoS Biol
Restrepo LJ, Graslie JK, Fortier TM, Baehrecke EH.   +3 more
europepmc   +1 more source

Heterogeneous metabolic response of endothelial cells from different vascular beds to experimental hyperglycaemia and metformin

The Journal of Physiology, EarlyView.
Abstract figure legend Diabetes mellitus is associated with vascular pathology that leads to vascular complications in several tissues, such as retinopathy of the eye. Endothelial dysfunction plays a pivotal role in the progression of each complication.
C. McAleese, G. Joudah, I. P. Salt, J. R. Petrie, J. M. Leiper, Laura B. Dowsett   +5 more
wiley   +1 more source

Mitophagy in the pathogenesis and management of disease. [PDF]

Cell Res
Wang Q, Sun Y, Li TY, Auwerx J.
europepmc   +1 more source

Role of Septin7 in mitochondrial dynamics and oxidative metabolism in C2C12 skeletal muscle cells

The Journal of Physiology, EarlyView.
Abstract figure legend Knockdown of Septin7 alters the expression of markers responsible for mitochondrial dynamics. Members of the electron transport chain are also affected by diminished Septin7 level resulting in functional changes of mitochondrial respiration. Abstract Mitochondria are dynamic organelles that undergo fusion and fission.
Andrea Telek, Ivett Gabriella Szabó, Anikó Keller‐Pintér, Mónika Gönczi, Eliza Guti, László Szabó, Brigitta Tillmann, Zoltán Márton Kohler, László Juhász, Péter Bai, Szilárd Póliska, Zsuzsanna Gaál, László Csernoch, János Fodor   +13 more
wiley   +1 more source

Parkin (PARK2) [PDF]

Science-Business eXchange, 2010
openaire   +3 more sources

Insights into PINK1/Parkin function and dysfunction from Drosophila models. [PDF]

Biochem J
Park S, Kozhushko N, Wight TH, Whitworth AJ.   +3 more
europepmc   +1 more source