Results 141 to 150 of about 226,005 (247)

The Development of Trait Anxiety in Nonhuman Primates During the First Year of Life

Developmental Science, Volume 29, Issue 2, March 2026.
ABSTRACT Anxious temperament (AT) is a nonhuman primate phenotype that models childhood behavioral inhibition, a prominent risk factor for anxiety disorders and stress‐related psychopathology. To understand its earliest antecedents, we characterized AT's developmental trajectory over the first year of life.
Rachel Puralewski, Nakul Aggarwal, Jonathan A. Oler, Patrick H. Roseboom, Lauren Parkins, Marissa K. Riedel, Carissa Boettcher, Ned H. Kalin   +7 more
wiley   +1 more source

Astragaloside IV inhibits MAPK pathway and promotes mitochondrial autophagy in rats with heart failure. [PDF]

Korean J Physiol Pharmacol
Wang Y, Chen Y, Li T, Zhong P, Wang Q.
europepmc   +1 more source

Surfacing Hidden Social Innovation for a Hidden Form of Flood Risk: The Story of Project Groundwater

Journal of Flood Risk Management, Volume 19, Issue 1, March 2026.
ABSTRACT Across the last decade ‘resilience’ has become a guiding principle for flood risk management (FRM) policymakers. The importance of the role of communities has been recognised, and there is a growing emphasis on innovation to contend with the complexity in community resilience building.
Karen Potter, Sarah Fitton
wiley   +1 more source

Mitophagy and oxidative stress in chronic kidney disease (Review). [PDF]

Mol Med Rep
Mushuo Q, Tian Y, Li J, Qiu Y, Fan H, Hu Q, Zhang Q.   +6 more
europepmc   +1 more source

Acoustic Sensing as a Tool for Brain Tumor Diagnostics

Advanced Sensor Research, Volume 5, Issue 2, February 2026.
Surface acoustic wave (SAW) sensing is used to distinguish non‐neoplastic brain tissue from primary and metastatic tumors based on their acoustic attenuation signatures. Ex vivo human brain samples reveal clear tissue‐specific mechanical profiles, correlating with stiffness and malignancy.
Melanie E. M. Stamp, Friederike Liesche‐Starnecker, Tina Schaller, Peter Baumgarten, Nadine Lilla, Dorothee Mielke, David Collins   +6 more
wiley   +1 more source

LGBT Rights-Focused Legal Advocacy in China: The Promise, and Limits, of Litigation [PDF]

, 2018
Siodhbhra Parkin
core   +1 more source

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

Advanced Science, Volume 13, Issue 7, 3 February 2026.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu, Qiqing Huang, Yang Liu, Jinzhuo Liu, Deyi Yang, Yanni Song, Xin Han   +6 more
wiley   +1 more source

Thonningianin A derived from Penthorum chinense Pursh alleviates cerebral ischemia/reperfusion-mediated apoptosis and pyroptosis through the activation of PINK1/Parkin-dependent mitophagy. [PDF]

Chin Med
Yao Q, Hu G, Yin C, Wu A, Hu G, Qin D, Zhou X, Law BY, Du X, Chen L, Li J, Lin H, Long X, Wu J, Yu L.   +14 more
europepmc   +1 more source

A Sirtuin‐1‐Targeted Gene‐Activating Tetrahedral DNA Attenuates Bladder Fibrosis by Restoring Mitophagy in Fibroblasts via the SIRT1‐FOXO3‐BNIP3 Axis

Advanced Science, Volume 13, Issue 8, 9 February 2026.
The SIRT1‐targeted saRNA‐delivering tetrahedral DNA (TSA) treatment effectively upregulates SIRT1 expression, which subsequently promotes FOXO3A deacetylation. This deacetylation event relieves FOXO3A's transcriptional repression on the BNIP3 gene, thereby initiating PINK1‐PARKIN‐dependent mitophagy.
Wei Wang, Ran Yan, Lede Lin, Lei Xiang, Xiaozhi Xia, Liao Peng, Xiaoshuai Gao, Jiawei Chen, Yang Xiong, Liang Zhou, Yunfeng Lin   +10 more
wiley   +1 more source

Mapping the global research landscape of mitophagy in Parkinson's disease: a bibliometric and visualization analysis. [PDF]

Hereditas
Zhao J, Wang Q, Cao Y, Shan H, Xu S.
europepmc   +1 more source