Results 151 to 160 of about 40,126 (261)

Ascetics, slaves, and necessity in Late Antiquity: renouncing all wealth, but for a single slave

Early Medieval Europe, EarlyView.
Slave owners in Late Antiquity viewed the possession of at least one slave to be a necessity and a defining mark that distinguished the dignified social classes from the poor. Ascetics who shared this perspective faced a choice when renouncing all worldly possessions in pursuit of spiritual perfection, one not merely about luxury, but also about status
E.T. Dailey, Justin Pigott
wiley   +1 more source

Muscone Promotes PINK1/Parkin-Associated Mitophagy to Suppress NLRP3 Inflammasome Activation: Implications for Endotoxemia Therapy. [PDF]

Pharmaceuticals (Basel)
Yan Z, Li M, Li D, Hua W, Cao H, Li Y, Che L, Chen X, Lai Z, Wang Y, Shen G, Qian J.   +11 more
europepmc   +1 more source

Response to equine cardiac adverse events during sports

Equine Veterinary Education, EarlyView.
Summary Cardiac adverse events and sudden death are a feared scenario for equine veterinarians, with serious consequences for animal health, riders' safety and the social licence to operate equestrian sports. The response to equine cardiac adverse events (CAEs) during sports is poorly defined.
C. Navas de Solis, J. Keen, A. Decloedt, B. Delvescovo, K. Hopster, K. Mitchell, J. Slack, G. van Loon, G. Van Steenkiste, L. Nath   +9 more
wiley   +1 more source

Mitophagy in ophthalmic pathologies: Molecular mechanisms and therapeutic implications. [PDF]

Medicine (Baltimore)
Han Y, Feng J, Gong X, Tang G, Yin Y, Li J, Liu Y, Zhang J, Song J, Bi H.   +9 more
europepmc   +1 more source

Exercise‐related microRNAs in Caenorhabditis elegans regulate calcium homeostasis and mitochondrial dynamics: Conserved pathways, divergent microRNAs

The FEBS Journal, EarlyView.
Exercise‐related microRNAs cel‐miR‐249‐3p and cel‐miR‐77‐5p in C. elegans regulate lifespan, fitness, mitochondrial morphology and membrane potential. Although lacking direct mammalian orthologs, H2O2‐induced microRNAs mmu‐miR‐181a‐5p and mmu‐miR‐378a‐3p regulate myogenesis, autophagy, mitochondrial content and respiration in murine myoblasts ...
Qin Xia, Jiwang Tang, José C. Casas‐Martinez, Penglin Li, Maria Borja‐Gonzalez, Leo R Quinlan, Katarzyna Goljanek‐Whysall, Brian McDonagh   +7 more
wiley   +1 more source

PTEN modulates mitochondrial dysfunction in podocytes via the PINK1/Parkin signal pathway. [PDF]

Transl Pediatr
Ren Q, Yu S.
europepmc   +1 more source

Mitochondrial transfer in acute myeloid leukaemia and multiple myeloma: Mechanisms, consequences and potential therapeutic opportunities

The FEBS Journal, EarlyView.
Mitochondria can be transferred from bone marrow cells to cancer cells in acute myeloid leukaemia and multiple myeloma, boosting tumour energy production, growth, and drug resistance. This review highlights key transfer mechanisms and shows how targeting mitochondrial movement and dynamics may offer new therapeutic strategies to limit cancer ...
Ebubechukwu Nwarunma, Mark T. S. Williams   +1 more
wiley   +1 more source

DAPK1-Mediated Parkin Inactivation Enhances Neurotoxicity via MITOL-Dependent Degradation. [PDF]

J Cell Mol Med
Park CH, Shin D, Chung KC.
europepmc   +1 more source

Ubiquitin and ubiquitin‐like modifications in the endoplasmic reticulum stress response

The FEBS Journal, EarlyView.
Endoplasmic reticulum (ER) stress activates various proteostasis control processes, including the unfolded protein response, ribosome‐associated quality control, and ER‐associated degradation. Ubiquitin and ubiquitin‐like modifications dynamically regulate these processes to determine cell fate, promoting adaptation or inducing cell death.
Tony Avril, Matthieu Le Gallo, Elodie Lafont   +2 more
wiley   +1 more source

Natural Product Treatment for Metabolic Dysfunction-Associated Steatotic Liver Disease: Targeted Mitochondrial Quality Control. [PDF]

Drug Des Devel Ther
Liu J, Li F, Zeng Q, Hu W, Yang L, Luo S, Lv F, Li D, Deng Y.   +8 more
europepmc   +1 more source