Results 171 to 180 of about 44,057 (302)

Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto, Phung N. Thai, Gabriela Grigorean, Veneese J. Brown, Tjien Dwyer, Nipavan Chiamvimonvat, Elena N. Dedkova, Saul Schaefer   +7 more
wiley   +1 more source

Mitophagy Activation via the YAP/Parkin Pathway Underlies the Neuroprotective Action of Tetramethylpyrazine in Cerebral Ischemia/Reperfusion Injury. [PDF]

Biomolecules
Xu L, Wang M, Feng Y, Wang S, Qian Y, Jiang W, Xu J, Fang Y, Zhang Y, Chu L.   +9 more
europepmc   +1 more source

家族性パーキンソン病原因遺伝子産物Parkin及びその酵母ホモログに関する分子生物学的研究 [PDF]

智義 小柳
openalex  

BSN (bassoon) and PRKN/parkin in concert control presynaptic vesicle autophagy [PDF]

, 2020
Carolina Montenegro‐Venegas, Anil Annamneedi, Sheila Hoffmann-Conaway, Eckart D. Gundelfinger, Craig C. Garner   +4 more
openalex   +1 more source

Neurodevelopmental and Psychiatric Studies in Children and Adolescents With Neurofibromatosis Type I: A Comprehensive Scoping Review

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 4, Page 257-269, June 2026.
ABSTRACT A comprehensive synthesis of the broad range of neurodevelopmental and psychiatric manifestations in NF1 is needed to identify knowledge gaps and future directions for NF1 research. In the following scoping review, we identify and summarize the scope of research that examines neurodevelopmental and psychiatric manifestations, both as ...
Meera Chopra, Tin‐Suet Joan Lee, Jacob Vorstman, Patricia Parkin, Louise Gallagher, Aneta Krakowski   +5 more
wiley   +1 more source

Cis or trans: a puzzle of Parkin activation mechanism. [PDF]

Essays Biochem
Sherawat M, Kumar A, Lenka DR, Kumar A.
europepmc   +1 more source

Homeobox B13 activates the hypoxia‐inducible factor 1 pathway through histone lactylation thereby reprogramming lipid metabolism and promoting sorafenib resistance in hepatocellular carcinoma

Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Lactylation‐mediated metabolism reprogramming in HCC sorafenib resistance. In sorafenib‐resistant hepatocellular carcinoma (HCC) cells, lactate accumulation drives histone H3 lysine 18 lactylation (H3K18la). This modification is specifically enriched in the promoter region of homeobox B13 (HOXB13), activating HOXB13 transcription and upregulating its ...
Qingqing Xie, Fangxia Teng, Ting Ding, Huaizhe Zhang, Jian Huang, Shu Zhang   +5 more
wiley   +1 more source

Malic enzyme 2 suppresses PINK1-Parkin-mediated mitophagy by stabilizing ATAD3A via competitive interaction with TRIM25. [PDF]

Cell Death Dis
Liu Q, Su L, Wei X, Lin S, Huang L, Hou L, Wang Y, Hu L, Tan J, Qiao J, Zhou Q, Ma Y, Wang W, Li J.   +13 more
europepmc   +1 more source

BMSC-Derived Exosomes Attenuate Rat Osteoarthritis by Regulating Macrophage Polarization through PINK1/Parkin Signaling Pathway [PDF]

Beibei Li, Enpu Shen, Zhiwen Wu, Hui Qi, Cheng’ai Wu, Danping Liu, Xu Jiang   +6 more
openalex   +1 more source

Quantitative Middle-Down MS Analysis of Parkin-Mediated Ubiquitin Chain Assembly

, 2020
Kirandeep K. Deol, Stephen J. Eyles, Eric R. Strieter   +2 more
openalex   +2 more sources