Results 181 to 190 of about 40,126 (261)

One day of environment‐induced heat stress causes injury to the murine kidney

Experimental Physiology, EarlyView.
Abstract Environment‐induced heat stress (EIHS) results from sustained body temperature elevation owing to prolonged exposure to heat and humidity. We hypothesized that EIHS would cause kidney injury and cellular dysfunction. To test this hypothesis, female C57 mice were exposed to EIHS (n = 14; 37.6°C, 42.0% relative humidity) or thermoneutral (TN ...
Melissa Roths, Alyona Michael, Zachary J. Schlader, Joshua T. Selsby   +3 more
wiley   +1 more source

Mitophagy-activating nanozyme hydrogel for enhanced diabetic wound healing. [PDF]

Mater Today Bio
Zhang J, Tang Z, Zhang X, Zhang H, He W.
europepmc   +1 more source

Mitophagy in skeletal muscle: Impact of ageing, exercise and disuse

Experimental Physiology, EarlyView.
Abstract Skeletal muscle plays an important role in whole‐body health, quality of life and regulation of metabolism. The maintenance of a healthy mitochondrial pool is imperative for the preservation of skeletal muscle quality and is mediated through mitochondrial quality control consisting of mitochondrial turnover mediated by a balance between ...
Anastasiya Kuznyetsova, David A. Hood
wiley   +1 more source

From homeostasis to pathology, organelle-specific autophagy in skeletal muscle: a PRISMA-ScR scoping review. [PDF]

Front Physiol
Wang C, Liu G, Guo C, Li Q, Wang F, Zhang M.   +5 more
europepmc   +1 more source

Effects of exercise in a fed or fasted state on mitochondrial dynamics regulators in the skeletal muscle of recreationally active males

Experimental Physiology, EarlyView.
Abstract Exercise and nutritional modulation favourably alter mitochondrial quantity and quality in skeletal muscle. Mitochondrial dynamics, the coordination of fission and fusion events, are poised to mediate key aspects of organelle adaptation that arise from exercise.
Elya J. Ritenis, Christos G. Stathis, Matthew B. Cooke, Stephen Keenan, Andrew Philp, Donny M. Camera   +5 more
wiley   +1 more source

Modulation of NFκB Signaling by Natural Compounds in Sarcoma and Normal Muscle Models. [PDF]

Int J Mol Sci
Radzka J, Gizak A, Baczyńska D, Junka A, Dudek B, Brożyna M, Szewczyk A, Kulbacka J.   +7 more
europepmc   +1 more source

Brain strain: Blood flow and metabolism in environmental extremes

Experimental Physiology, EarlyView.
Abstract This narrative review compares and contrasts the most commonly encountered environmental stressors on human cerebrovascular functioning. From high altitude and space, extreme apnoea, heat and cold stress, the impact of these stressors on the regulation of cerebral blood flow (CBF) and oxygen metabolism (CMRO2${\mathrm{CM}}{{\mathrm{R}}_ ...
Dario Vrdoljak, Damian M. Bailey, Travis D. Gibbons, Philip N. Ainslie   +3 more
wiley   +1 more source

Mitophagy in kidney and lung epithelial cells: molecular mechanisms, crosstalk, and therapeutic interventions. [PDF]

Front Physiol
Zhou X, Sun J, Miao L, Zhang Y.
europepmc   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Enterovirus-induced cleavage of Mitofusin 2 generates mitophagosomes for enveloped virion release. [PDF]

Sci Adv
Jassey A, Paudel B, Wagner MA, Pollack N, Cheng IT, Godoy-Ruiz R, Weber DJ, Jackson WT.   +7 more
europepmc   +1 more source