Results 1 to 10 of about 9,647,508 (315)

Parkinson’s disease: etiopathogenesis and treatment

Journal of Neurology Neurosurgery & Psychiatry, 2020
The concept of ‘idiopathic’ Parkinson’s disease (PD) as a single entity has been challenged with the identification of several clinical subtypes, pathogenic genes and putative causative environmental agents.
J. Jankovic, E. Tan
semanticscholar   +1 more source

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease

Nature Genetics, 2014
We conducted a meta-analysis of Parkinson's disease genome-wide association studies using a common set of 7,893,274 variants across 13,708 cases and 95,282 controls. Twenty-six loci were identified as having genome-wide significant association; these and
M. Nalls, N. Pankratz, C. Lill, Chuong B. Do, D. Hernandez, D. Hernandez, M. Saad, M. Saad, M. Saad, A. Destefano, A. Destefano, E. Kara, J. Bras, Manu Sharma, C. Schulte, Margaux F. Keller, S. Arepalli, Christopher T Letson, Connor Edsall, H. Stefánsson, Xinmin Liu, Hannah A. Pliner, Joseph H. Lee, R. Cheng, M. Ikram, J. Ioannidis, G. Hadjigeorgiou, J. Bis, Miguel Ángel Martínez, Miguel Ángel Martínez, J. Perlmutter, A. Goate, K. Marder, B. Fiske, Margaret Sutherland, G. Xiromerisiou, R. Myers, L. Clark, K. Stefánsson, J. Hardy, P. Heutink, Honglei Chen, N. Wood, H. Houlden, H. Payami, A. Brice, A. Brice, W. Scott, T. Gasser, L. Bertram, N. Eriksson, T. Foroud, A. Singleton   +52 more
semanticscholar   +1 more source

Current and projected future economic burden of Parkinson’s disease in the U.S.

npj Parkinson's Disease, 2020
Parkinson’s disease (PD) is one of the world’s fastest growing neurological disorders. Much is unknown about PD-associated economic burdens in the United States (U.S.) and other high-income nations.
Wenya Yang, J. Hamilton, C. Kopil, J. Beck, C. Tanner, R. Albin, E. Ray Dorsey, N. Dahodwala, Inna Cintina, P. Hogan, Ted Thompson   +10 more
semanticscholar   +1 more source

Prevalence of Parkinson’s disease across North America

npj Parkinson's Disease, 2018
Estimates of the prevalence of Parkinson’s disease in North America have varied widely and many estimates are based on small numbers of cases and from small regional subpopulations.
C. Marras, J. Beck, J. Bower, E. Roberts, B. Ritz, G. Ross, R. Abbott, R. Savica, S. K. Van Den Eeden, A. Willis, C.M. Tanner, on behalf of the Parkinson’s Foundation P4 Group   +11 more
semanticscholar   +1 more source

Genome-Wide Association Study reveals genetic risk underlying Parkinson’s disease

Nature Genetics, 2009
We performed a genome-wide association study (GWAS) in 1,713 individuals of European ancestry with Parkinson's disease (PD) and 3,978 controls. After replication in 3,361 cases and 4,573 controls, we observed two strong association signals, one in the ...
J. Simón-Sánchez, C. Schulte, J. Bras, Manu Sharma, J. R. Gibbs, Daniela Berg, C. Paisán-Ruiz, Peter Lichtner, S. Scholz, Dena G. Hernandez, Rejko Krüger, Monica Federoff, C. Klein, Alison Goate, Joel Perlmutter, Michael Bonin, Michael A. Nalls, T. Illig, C. Gieger, H. Houlden, Michael Steffens, M. S. Okun, B. Racette, M. Cookson, K. Foote, Hubert H. Fernandez, Bryan J. Traynor, S. Schreiber, S. Arepalli, Ryan R. Zonozi, Katrina Gwinn, M. V. D. Brug, Grisel Lopez, S. Chanock, A. Schatzkin, Yikyung Park, A. Hollenbeck, Jianjun Gao, Xuemei Huang, Nick W. Wood, D. Lorenz, Günther Deuschl, Honglei Chen, Olaf Riess, John A Hardy, A. Singleton, Thomas Gasser   +46 more
semanticscholar   +1 more source

[Parkinson's disease].

La Revue du praticien, 2022
Houeto Jean-Luc
semanticscholar   +1 more source

Parkinson’s Disease Is Predominantly an Environmental Disease

Journal of Parkinson's Disease
Parkinson’s disease is the world’s fastest growing brain disorder, and exposure to environmental toxicants is the principal reason. In this paper, we consider alternative, but unsatisfactory, explanations for its rise, including improved diagnostic ...
E. Dorsey, Bastiaan R. Bloem, MD Ray Dorsey   +2 more
semanticscholar   +1 more source

MDS clinical diagnostic criteria for Parkinson's disease

Movement Disorders, 2015
R. Postuma, D. Berg, M. Stern, W. Poewe, C. Olanow, W. Oertel, J. Obeso, K. Marek, I. Litvan, A. Lang, G. Halliday, C. Goetz, T. Gasser, B. Dubois, P. Chan, B. Bloem, C. Adler, G. Deuschl   +17 more
semanticscholar   +1 more source

Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases.

Journal of Neurology Neurosurgery & Psychiatry, 1992
A. Hughes, S. Daniel, L. Kilford, A. J. Lees, London Wcln, J. Hughes   +5 more
semanticscholar   +1 more source

Challenges in the diagnosis of Parkinson's disease

Lancet Neurology, 2021
E. Tolosa, Alicia Garrido, Sonja W. Scholz, W. Poewe   +3 more
semanticscholar   +1 more source