Results 1 to 10 of about 240,015 (160)
The Lancet, 2021 Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; the rising prevalence worldwide resembles the many characteristics typically observed during a pandemic, except for an infectious cause.
Bloem, B.R., Okun, M.S., Klein, C.
openaire +2 more sources
Progress Notes : a report from the Parkinson's Disease Center at Boston University Medical Center [PDF]
, 1989 News and updates from the Boston University Medical Center, Parkinson's Disease ...
Parkinson's Disease Center at Boston University Medical Center
core +11 more sources
The Lancet, 2004 Parkinson's disease is the most common serious movement disorder in the world, affecting about 1% of adults older than 60 years. The disease is attributed to selective loss of neurons in the substantia nigra, and its cause is enigmatic in most individuals.
Samii, Ali +2 more
openaire +3 more sources
Familial Parkinson’s Disease/Parkinsonism [PDF]
BioMed Research International, 2015 Parkinson's disease (PD) is the second most common neurodegenerative disorder characterized by parkinsonism (bradykinesia, resting tremor, rigidity, and postural instability) with good response to L-dopa. Although the majority of PD patients are sporadic, it is now clear that genetic factors contribute to the pathogenesis of PD.
Hiroyuki Tomiyama +3 more
openaire +3 more sources
Annals of Indian Academy of Neurology, 2011 These guidelines present evidence for interventions to manage early stage, uncomplicated Parkinson's Disease. This includes pharmacological and non-pharmacological interventions. The evidence for pharmacological agents to provide neuroprotection or disease modification, such as a delay in disease progression, is discussed, with no trials demonstrating ...
Behari, Madhuri +11 more
openaire +8 more sources
Parkinson’s Disease and Autophagy [PDF]
Parkinson's Disease, 2012 It is generally accepted that a correlation between neurodegenerative disease and protein aggregation in the brain exists; however, a causal relationship has not been elucidated. In neurons, failure of autophagy may result in the accumulation of aggregate-prone proteins and subsequent neurodegeneration.
Ana María Sánchez-Pérez +5 more
openaire +5 more sources
Deletions at 22q11.2 in idiopathic Parkinson's disease: a combined analysis of genome-wide association data. [PDF]
, 2016 BACKGROUND: Parkinson's disease has been reported in a small number of patients with chromosome 22q11.2 deletion syndrome. In this study, we screened a series of large, independent Parkinson's disease case-control studies for deletions at 22q11.2 ...
Abramov, Andrey Y +38 more
core +3 more sources
Rare coding SNP in DZIP1 gene associated with late-onset sporadic Parkinson's disease [PDF]
, 2011 We present the first application of the hypothesis-rich mathematical theory to genome-wide association data. The Hamza et al. late-onset sporadic Parkinson's disease genome-wide association study dataset was analyzed.
A Lerner +47 more
core +3 more sources
How do I sound to me? Perceived changes in communication in Parkinson's disease [PDF]
, 2007 Objective: To examine self and carer perceived changes in communication associated with Parkinson's disease and relate these to speech intelligibility, gender, age and other disease measures.
Bosworth H. +9 more
core +1 more source
What contributes to depression in Parkinson's disease? [PDF]
, 2001 Background: Depression is a common problem in patients with Parkinson's disease, but its mechanism is poorly understood. It is thought that neurochemical changes contribute to its occurrence, but it is unclear why some patients develop depression and ...
Jahanshahi, M., Quinn, N.P., Schrag, A.
core +1 more source