Results 151 to 160 of about 43,444 (242)
Pathology and Genetics in a Global Cohort of Parkinsonian Disorders.
Wu LY +40 more
europepmc +1 more source
Biomarker bust: meta-analyses reveal unreliability of neuronal extracellular vesicles for diagnosing parkinsonian disorders. [PDF]
Taha HB.
europepmc +1 more source
Neuropathological correlates of parkinsonian disorders in a large Dutch autopsy series. [PDF]
Geut H +6 more
europepmc +1 more source
A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento +3 more
wiley +1 more source
Two distinct degenerative types of nigrostriatal dopaminergic neuron in the early stage of parkinsonian disorders. [PDF]
Kawazoe T +4 more
europepmc +1 more source
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim +4 more
wiley +1 more source
Magnetic Resonance Imaging and Nuclear Imaging of Parkinsonian Disorders: Where do we go from here? [PDF]
Savoie FA, Arpin DJ, Vaillancourt DE.
europepmc +1 more source
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee +10 more
wiley +1 more source

