Results 171 to 180 of about 65,290 (261)
Detection and differentiation of ataxic and hypokinetic dysarthria in cerebellar ataxia and parkinsonian disorders via wave splitting and integrating neural networks. [PDF]
Song J +13 more
europepmc +1 more source
Abstract Deep brain stimulation (DBS) effectively treats motor symptoms in movement disorders but often compromises speech through incompletely defined mechanisms. We conducted a PROSPERO‐registered systematic review and meta‐analysis of publications through August 2024 (CRD42024527738).
Elina Tripoliti +15 more
wiley +1 more source
Refining the diagnostic accuracy of Parkinsonian disorders using metaphenomic annotation of the clinicopathological literature. [PDF]
Massey Q +6 more
europepmc +1 more source
ABSTRACT Background Dopa‐responsive dystonia is caused by pathogenic variants in the GCH1 gene. Although its clinical features and reduced penetrance are known, in vivo metabolic and structural alterations in symptomatic (sMC) and asymptomatic mutation carriers (aMC) remain poorly understood.
Jannik Prasuhn +12 more
wiley +1 more source
Levodopa exposure and nigral neuroinflammation in parkinsonian disorders: A postmortem study of 63 cases. [PDF]
Backman EA +4 more
europepmc +1 more source
Abstract Background Differentiating progressive supranuclear palsy (PSP) from Parkinson's disease (PD) can be clinically challenging. In the neuroimaging field, radiomics has emerged as a promising approach to capture subtle microstructural and textural image alterations, improving differential diagnoses.
Chiara Camastra +8 more
wiley +1 more source
Moving beyond the hospital: in-depth characterization of daily-life mobility in patients with atypical Parkinsonian disorders. [PDF]
Sidoroff V +23 more
europepmc +1 more source
Abstract Background Parkinson's disease (PD) is clinically heterogeneous, with substantial variability in motor and cognitive features. Conventional clinical scales provide limited insight into underlying neural mechanisms and show poor longitudinal stability.
Daniel Vered +4 more
wiley +1 more source
NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics. [PDF]
Chiang HL +7 more
europepmc +1 more source

