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Cerebrospinal Fluid Levels of Neurogranin in Parkinsonian Disorders
Movement Disorders, 2019AbstractBackgroundCSF concentration of neurogranin has been suggested as a biomarker for synapse dysfunction.ObjectivesTo investigate CSF neurogranin in parkinsonian disorders compared to controls and Alzheimer's disease and the possible correlations between neurogranin and cognitive and motor impairment.MethodsWe included 157 patients with PD, 29 with
Hall, S +7 more
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Transcranial sonography in parkinsonian disorders
2021Parkinson's disease is extremely difficult to diagnose, given that no test provides conclusive evidence for the disease. Many patients in the early stages of the disease have very few symptoms or experience symptoms that overlap with other conditions that resemble Parkinson's disease, known as parkinsonian disorders.
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Recent advances in atypical parkinsonian disorders
Current Opinion in Neurology, 1999Recent advances in epidemiologic, diagnostic, pathologic, and management aspects of atypical parkinsonian disorders are reviewed and placed in perspective. The implications of considering progressive supranuclear palsy and corticobasal degeneration as tauopathies, and multiple system atrophy and dementia with Lewy bodies as alpha-synucleopathies are ...
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Disorders of Intention in Parkinsonian Syndromes
2003In recent years, the symptom of akinesia in parkinsonism has provided a valuable window into the physiological substrate of voluntary movement in man, particularly the role of the basal ganglia and the influence of dopamine. In a similar way, the study of individual nonmotor symptoms in parkinsonism can provide insights into the subsystems underlying ...
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α-Synuclein seed amplification assay as a diagnostic tool for parkinsonian disorders
Parkinsonism and Related Disorders, 2023Radu Constantinescu +2 more
exaly
What is an Atypical Parkinsonian Disorder?
2005A parkinsonism is a syndrome defined by akinesia associated with rigidity or rest tremor. The akinesia can be expressed as motor slowness (bradykinesia) or as a paucity of movement (hypokinesia), i.e., difficulty in the initiation of or decreased amplitude of movements such as arm swing or facial expression.
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Parkinsonian Disorders in Clinical Practice
2009This book gives the reader an up-to-date, clear and logical idea of what caring for parkinsonian patients entails - a challenge that clinicians will face for ...
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Neuropathology of Atypical Parkinsonian Disorders
2005Although the clinical syndrome of parkinsonism (rigidity, bradykinesia, and tremor) is most often owing to idiopathic Parkinson’s disease (PD), it may also be associated with a variety of other underlying pathologies (Table 1) (1, 2, 3). Each of these other pathological conditions tends to have a characteristic clinical phenotype, however atypical ...
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Autonomic dysregulation during sleep in Parkinsonian spectrum disorders - A proof of concept
Parkinsonism and Related Disorders, 2023Daniel Levendowski +2 more
exaly