Results 181 to 190 of about 43,444 (242)

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, Volume 4, Issue 2, Page 99-110, June 2026.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Bee venom enhances dopaminergic function and behavioral recovery in a murine model of Parkinson's disease

Neuroprotection, Volume 4, Issue 2, Page 169-177, June 2026.
Experimental design and behavioral outcomes of bee venom treatment in a murine model of Parkinson's disease. Mice received an intrastriatal injection of 6‐OHDA into the right hemisphere to induce dopaminergic degeneration. Animals were subsequently treated with l‐DOPA/carbidopa, with or without bee venom (BV) administered intraperitoneally.
Silvia Josefina López‐Pérez, Marco Antonio Noriega‐Ruiz, Alma Karen Lomeli‐Lepe   +2 more
wiley   +1 more source

High Adherence to Pharmacological Treatment Guidelines in Recovery and Remission States Among Patients With Schizophrenia: A Cross‐Sectional Study

Neuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
Guideline‐adherent pharmacotherapy (Individual Fitness Score: IFS) was higher in recovery and remission than in non‐remission in schizophrenia (≈88–89 vs. 66; p < 0.01). An IFS cutoff of 72 discriminated remission from non‐remission. Findings suggest adherence may support favorable clinical states, though the cutoff is preliminary (small sample, cross ...
Ryo Asada, Hitoshi Iida, Leo Gotoh, Kiyohiro Yasumatsu, Hikaru Hori   +4 more
wiley   +1 more source

The importance of longitudinal evaluation using DAT‐SPECT in organophosphate‐induced toxic parkinsonism

Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao, Yoichiro Kogoh, Hideki Funahashi, Yusei Yanoma, Minako Azuma, Yasushi Ishida, Yoji Hirano   +6 more
wiley   +1 more source

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto, Lucia Buccarello, Giuseppe Carota, Rocco Salvatore Calabrò, Carmela Rifici, Emanuela Esposito, Alessio Ardizzone, Giuseppe Caruso   +7 more
wiley   +1 more source

What Is the StartReact Effect?

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT The use of a startling acoustic stimulus during a simple reaction time task results in the rapid initiation of a prepared response at extremely short latencies (< 80 ms). This so‐called “StartReact effect” has been increasingly employed to probe subcortical contributions to response preparation, as it is thought to occur due to increased ...
Anthony N. Carlsen, Dana Maslovat
wiley   +1 more source

Diagnostic Value of Bedside Eye Movement Examination in Movement Disorders

Movement Disorders Clinical Practice, Volume 13, Issue 6, Page 1577-1578, June 2026.
Eloísa Bittencurt Thomaz de Assis, Paula Martínez Ruiz, Cristina Acosta Gudiel, Hüseyin Nezih Özdemir, Diego Kaski   +4 more
wiley   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Sex‐Dependent Effects of CSF1R‐Mediated Myeloid Cell Depletion in a Mouse Model of Multiple System Atrophy

European Journal of Neuroscience, Volume 63, Issue 12, June 2026.
Myeloid cell depletion in males is rapid and initially more effective than in females, which leads to reduced occurrence of dystonia‐like neurological symptoms and alleviated neuronal loss in a mouse model of MSA. Overall, these findings indicate that the therapeutic efficacy of CSF1R‐mediated myeloid cell depletion in MSA is sex‐specific. ABSTRACT Sex‐
Kristina Battis, Michael Mante, Isabel Naumann, Marie Andert, Ha Yeon Kim, Wei Xiang, Robert A. Rissman, Jürgen Winkler, Alana Hoffmann   +8 more
wiley   +1 more source

Deciphering Freezing of Gait: What Neuropathology Reveals About an Episodic Phenomenon

European Journal of Neuroscience, Volume 63, Issue 12, June 2026.
Freezing of gait (FoG) occurs across Parkinson's disease, multiple neurodegenerative conditions and non‐neurodegenerative disorders. This review synthesizes the structural, neurochemical and proteinopathic substrates underlying FoG, showing how cumulative damage to distributed locomotor circuits—compounded by overlapping pathologies—progressively ...
Gabor G. Kovacs
wiley   +1 more source