Results 1 to 10 of about 176,756 (350)

P433: PHARMACOLOGICAL DUAL INHIBITION OF PARP AND TIP60 AS A PROSPECTIVE THERAPEUTIC REGIMEN INDUCES SYNERGISTIC AML CELL DEATH

, 2023
Tae Ju Park, Helen Wheadon, Laura Monaghan, Xu Huang, Heather G. Jørgensen   +4 more
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Sequential Inhibition of PARP and WEE1 Minimizes Toxicity [PDF]

, 2019

openalex   +1 more source

PARP-2 catalytic activity drives replication-ICL repair in an allele-specific manner during germline development. [PDF]

PLoS Genet
Ren X, Hu A, Liu Z, Kim S, Kim HM.
europepmc   +1 more source

The CDK1 inhibitor RO3306 improves the response of BRCA-proficient breast cancer cells to PARP inhibition

, 2013
Qing Xia, Yuchen Cai, Roujun Peng, Guosheng Wu, Yanxia Shi, Wenqi Jiang   +5 more
openalex   +2 more sources

First report on chlorophyllin to protect mammalian and fish muscle cells from pesticide toxicity via activation of p53 and PARP

, 2020
Asmita Samadder, Swatilekha Das, B. C. Pal, Sweta Das, Anindita Mandal, Priyanka Biswas, Sujoy Ghosh, Shamim Hossain Mandal, Priyanka Sow, Ruchira Das, Souvik Biswas, Ashis Kumar Panigrahi   +11 more
openalex   +1 more source

PARP Inhibitors in Cancer Therapy: Magic Bullets but Moving Targets [PDF]

, 2013
Girish M. Shah, Mihaela Robu, Nupur K. Purohit, Jyotika Rajawat, Lucio Tentori, Grazia Graziani   +5 more
openalex   +1 more source

MOB2 Loss Sensitizes Lung Cancer Cells to PARP Inhibition Through p53-Dependent DNA Damage Signaling. [PDF]

Curr Issues Mol Biol
Gundogdu R.
europepmc   +1 more source

Differential modulation of haematopoietic and oxidative injury by PARP-1 and ATR kinase inhibition in a murine model of acute irradiation. [PDF]

PLoS One
Sih BT.
europepmc   +1 more source

Challenges in employing overall survival as a primary outcome in ovarian cancer studies: insights from PARP inhibitor trials. [PDF]

Front Oncol
Siegler Y, Matanes E.
europepmc   +1 more source

Author response: Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment

Youyou Zhang, Mu Xu, Jiao Yuan, Zhongyi Hu, Junjie Jiang, Yanrong Sun, Jie Huang, Yuxin Wang, Bingwei Wang, Jianfeng Shen, Meixiao Long, Yi Fan, Kathleen T. Montone, János L. Tanyi, Sarah H Kim, Omid Tavana, Robert H. Vonderheide, Ho Man Chan, Susan M. Domchek, Xiaowen Hu, Lin Zhang   +20 more
openalex   +1 more source