Results 131 to 140 of about 116,902 (309)
International Journal of Cancer, EarlyView.The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg +9 more
wiley +1 more source
International Journal of Cancer, EarlyView.Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger +13 more
wiley +1 more source
Western blot analysis for poly(ADP-ribose)polymerase (PARP) protein expression in mammary tumor (MT)
, 2011 Copyright information:Taken from "Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice"http://breast-cancer-research.com/content/9/6/R91Breast Cancer Research : BCR 2007;9(6):R91-R91 ...
Xin Hu (38924) +5 more
core +1 more source
International Journal of Cancer, EarlyView.Molecular tumor boards (MTB), interdisciplinary teams that use tumor genomic data to guide personalized treatment decisions, have emerged as a promising strategy in melanoma care, although their real‐world clinical impact remains uncertain. This retrospective study evaluated advanced melanoma patients to assess molecularly guided treatment ...
Glenn Geidel +26 more
wiley +1 more source
The clinical significance of serum PARP-1 protein high expression in gastric cancer
Zhongguo aizheng zazhi, 2015 Background and purpose: PARP-1 is closely related to malignant tumors. This study aimed to explore the clinical significance of serum level of PARP-1 protein in onset and progression of gastric cancer.
王 睿, 王 岚, 黎明新
doaj
International Journal of Cancer, EarlyView.While current guidelines recommend the analysis of established cancer driver genes in brain metastases, little is known about its real‐life implementation. This multicenter study revealed an upward trend in the profiling rates of surgically treated brain metastases over the past decade, with up to 60% of brain metastases samples undergoing analysis ...
Maria Nikolaeva +25 more
wiley +1 more source
PARP-1 is a transcriptional rheostat of metabolic and bivalent genes during development
Life Science AlliancePARP-1 fine-tunes gene expression to control energy balance and development by selectively repressing and activating critical genes for developmental progression. PARP-1 participates in various cellular processes, including gene regulation. In Drosophila
Gbolahan Bamgbose, Alexei Tulin
doaj +1 more source
, 2011 Copyright information:Taken from "Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice"http://breast-cancer-research.com/content/9/6/R91Breast Cancer Research : BCR 2007;9(6):R91-R91 ...
Xin Hu (38924) +5 more
core +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao +5 more
wiley +1 more source
The effects of PARP inhibitors in the imiquimod-induced mouse model of psoriasis
A pikkelysömör egy krónikus gyulladásos bőrbetegség, amelyben a keratinociták fokozott proliferációja és zavart differenciációja figyelhető meg. A poli(ADP-ribóz) polimeráz (PARP) enzimek fontos szerepet játszanak a gyulladásos folyamatok szabályozásában,
Takács, Mátyás
core