Results 261 to 270 of about 742,291 (286)

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

Cancer Cell, 2018
Zhenlin Ju, Jun Yin
exaly  

Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy

Cancer Cell, 2019
Ken Chen, Zhenlin Ju, Gordon B. Mills
exaly  

Enhancing the Cytotoxic Effects of PARP Inhibitors with DNA Demethylating Agents – A Potential Therapy for Cancer

Cancer Cell, 2016
Michael M Seidman, Feyruz V Rassool, Pratik K Nagaria   +2 more
exaly  

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

Cell, 2018
Jiří Lukáš, Takeo Narita, André Stanlie   +2 more
exaly  

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality

Cancer Cell, 2018
Marieke van de Ven, Haico van Attikum, Marcel A.T.M. van Vugt   +2 more
exaly  

Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors

Cancer Cell, 2020
Meng Yu, Lin Li, Chen Li
exaly  

POTENT PARP INHIBITORS

2009
PENNING THOMAS D, THOMAS SHEELA A, HAJDUK PHILIP J, SAUER DARYL R, SARRIS KATHY, GIRANDA VINCENT L   +5 more
openaire   +2 more sources

PARP inhibitors in ovarian cancer: Sensitivity prediction and resistance mechanisms

Journal of Cellular and Molecular Medicine, 2019
Weihua Li, Ying Feng, Huimin Bai
exaly  

Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer

Annals of Oncology, 2017
Gordon B. Mills, David B Solit
exaly  

Pyrazoloquinolones are potent parp inhibitors

2007
PENNING THOMAS D, ZHU GUI-DONG, GANDHI VIRAJKUMAR B, GONG JIANCHUN, GIRANDA VINCENT L   +4 more
openaire   +5 more sources