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PARP Inhibitors as Therapeutics: Beyond Modulation of PARylation
Cancers, 2020 Poly (ADP-ribose) polymerase (PARP) 1 is an essential molecule in DNA damage response by sensing DNA damage and docking DNA repair proteins on the damaged DNA site through a type of posttranslational modification, poly (ADP-Ribosyl)ation (PARylation ...
Seock-Ah Im, Min Ahrum, Im Seock-Ah
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Understanding and overcoming resistance to PARP inhibitors in cancer therapy
Nature Reviews Clinical Oncology, 2021Mariana Paes Dias +2 more
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Poly(ADP-Ribose) polymerase (PARP) inhibitors: Exploiting a synthetic lethal strategy in the clinic
Ca-A Cancer Journal for Clinicians, 2011Timothy A Yap +2 more
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<p>PARP Inhibitors in Endometrial Cancer: Current Status and Perspectives</p>
Cancer Management and Research, 2020Lucia Musacchio +2 more
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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy
Cancer Cell, 2019Daniel J Mcgrail +2 more
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PARP inhibitors: Clinical utility and possibilities of overcoming resistance
Gynecologic Oncology, 2017Benjamin G Bitler +2 more
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