Results 71 to 80 of about 66,774 (189)

Parvalbumin Neurons in Zona Incerta Regulate Itch in Mice

open access: yesFrontiers in Molecular Neuroscience, 2022
Pain and itch are intricately entangled at both circuitry and behavioral levels. Emerging evidence indicates that parvalbumin (PV)-expressing neurons in zona incerta (ZI) are critical for promoting nocifensive behaviors.
Jiaqi Li   +11 more
doaj   +1 more source

Simplified three-dimensional tissue clearing and incorporation of colorimetric phenotyping. [PDF]

open access: yes, 2016
Tissue clearing methods promise to provide exquisite three-dimensional imaging information; however, there is a need for simplified methods for lower resource settings and for non-fluorescence based phenotyping to enable light microscopic imaging ...
Chen, Harrison   +12 more
core   +2 more sources

Deficits in high- (>60 Hz) gamma-band oscillations during visual processing in schizophrenia [PDF]

open access: yes, 2013
Current theories of the pathophysiology of schizophrenia have focused on abnormal temporal coordination of neural activity. Oscillations in the gamma-band range (>25 Hz) are of particular interest as they establish synchronization with great precision in
Christine eGruetzner   +7 more
core   +5 more sources

Metal-controlled interdomain cooperativity in parvalbumins [PDF]

open access: yesCell Calcium, 2009
Conformational behavior of five homologous proteins, parvalbumins (PAs) from northern pike (alpha and beta isoforms), Baltic cod, and rat (alpha and beta isoforms), was studied by scanning calorimetry, circular dichroism, and bis-ANS fluorescence. The mechanism of the temperature-induced denaturation of these proteins depends dramatically on both the ...
Permyakov, Sergei E.   +5 more
openaire   +3 more sources

Cell-type-specific control of basolateral amygdala neuronal circuits via entorhinal cortex-driven feedforward inhibition

open access: yeseLife, 2020
The basolateral amygdala (BLA) plays a vital role in associating sensory stimuli with salient valence information. Excitatory principal neurons (PNs) undergo plastic changes to encode this association; however, local BLA inhibitory interneurons (INs ...
E Mae Guthman   +7 more
doaj   +1 more source

The cellular and synaptic architecture of the mechanosensory dorsal horn [PDF]

open access: yes, 2017
The deep dorsal horn is a poorly characterized spinal cord region implicated in processing low-threshold mechanoreceptor (LTMR) information. We report an array of mouse genetic tools for defining neuronal components and functions of the dorsal horn LTMR ...
Abraira   +80 more
core   +1 more source

Tourette syndrome research highlights from 2016 [version 1; referees: 3 approved, 1 approved with reservations] [PDF]

open access: yes, 2017
This article presents highlights chosen from research that appeared during 2016 on Tourette syndrome and other tic disorders.
Black, Kevin J
core   +3 more sources

Parvalbumins from the lungfish (Protopterus dolloi) [PDF]

open access: yesBiochimie, 1979
Five parvalbumins have been isolated from the white muscles of the lungfish. They can be divided into two sub families showing typical amino acid compositions, C-terminal amino acid residues, peptide maps and immuno-reactivity. The red muscles including the cardiac muscle also contain parvalbumins in amounts roughly inversely related to the ...
Gerday, Charles   +4 more
openaire   +2 more sources

Increased Dendritic Branching of and Reduced δ-GABAA Receptor Expression on Parvalbumin-Positive Interneurons Increase Inhibitory Currents and Reduce Synaptic Plasticity at Puberty in Female Mouse CA1 Hippocampus

open access: yesFrontiers in Cellular Neuroscience, 2020
Parvalbumin positive (PV+) interneurons play a pivotal role in cognition and are known to be regulated developmentally and by ovarian hormones. The onset of puberty represents the end of a period of optimal learning when impairments in synaptic ...
Hui Shen   +5 more
doaj   +1 more source

Interneuron Development Is Disrupted in Preterm Brains With Diffuse White Matter Injury: Observations in Mouse and Human

open access: yesFrontiers in Physiology, 2019
Preterm brain injury, occurring in approximately 30% of infants born <32 weeks gestational age, is associated with an increased risk of neurodevelopmental disorders, such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder ...
Helen B. Stolp   +18 more
doaj   +1 more source

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