Results 101 to 110 of about 6,567 (153)

Role of poly(ADP-ribosyl)ation in a 'two-hit' model of hypoxia and oxidative stress in human A549 epithelial cells in vitro [PDF]

, 2017
Erdélyi, Katalin, Pacher, Pál, Szabó, Csaba, Virág, László   +3 more
core   +1 more source

PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB-RNAPII complex. [PDF]

Nucleic Acids Res
Robu M, Shah RG, van den Heuvel D, Coulombe Y, Bazin M, van der Woude M, Kragten A, Lans H, Pascal JM, Masson JY, Luijsterburg MS, Shah GM.   +11 more
europepmc   +1 more source

Chromatin relaxation dynamics and histone PTMs in the early DNA damage response. [PDF]

Cancer Biol Med
Qian J, Xie Z, Zhou L, Zhu WG.
europepmc   +1 more source

Poly(ADP-ribose) polymerase (PARP) inhibitors in cardiovascular, and cerebrovascular diseases: mechanisms, current trends and challenge for clinical translation. [PDF]

PeerJ
Fan J, Song Y.
europepmc   +1 more source

Interaction between Poly(ADP-ribose) polymerase-1 and α-synuclein pathology in Parkinson's disease. [PDF]

Front Neurosci
Zhang P, Li Q, Diao X, Zeng S.
europepmc   +1 more source

PARG inhibition suppresses breast cancer progression and potentiates immunoresponse through MTDH degradation mediated by E3 ligase ITCH-dependent ubiquitination. [PDF]

NPJ Breast Cancer
Wang J, Dong Y, Lun W, Nai M, Shi Y, Geng J, Cai W, Liu J, Li H, Li L.   +9 more
europepmc   +1 more source

Glioblastoma and PARP inhibitors: the importance of patient selection to maximize therapeutic benefits. A critical review. [PDF]

Front Oncol
Dima G, Di Nunno V, Aprile M, Gatto L, Tosoni A, Argento CM, Margotti M, Bartolini S, Franceschi E.   +8 more
europepmc   +1 more source

Targeting m⁶A RNA methylation to sensitize cancer cells to DNA-damaging therapies. [PDF]

Discov Oncol
Cesaro B, Venezia S, Tarullo M, Piscopo F, Fatica A.   +4 more
europepmc   +1 more source

Genetic evidence for PARP1 trapping as a driver of PARP inhibitor efficacy in BRCA mutant cancer cells. [PDF]

Nucleic Acids Res
Ribeiro J, Hansen K, van Beek L, Stubbs C, Frigola J, Talbot S, Bentouati S, Hall J, Wijnhoven PWG, Armenia J, Schimpl M, Forment JV, Albertella MR, O'Connor MJ, Illuzzi G.   +14 more
europepmc   +1 more source

Poly(ADP-ribose) glycohydrolase enforces p21 degradation via dePARylation to promote gastric cancer progression. [PDF]

J Clin Invest
Hu Y, Bao Q, Huang Y, Wang Y, Zhao X, Nan J, Meng Y, Deng M, Li Y, Zhuang Z, He H, Zu D, Zhong Y, Zhang C, Wang B, Li R, He Y, Wang Q, Liu M, Tainer JA, Shi Y, Cheng X, Jing J, Ye Z.   +23 more
europepmc   +1 more source