Results 111 to 120 of about 1,147 (142)
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Catalytic Enantioselective Isocyanide‐Based Reactions: Beyond Passerini and Ugi Multicomponent Reactions

Chemistry – A European Journal, 2021
AbstractThe development of catalytic enantioselective isocyanide‐based reactions is currently of great interest because the resulting products are valuable in organic synthesis, pharmacological chemistry, and materials science. This review assembles and comprehensively summarizes the recent achievements in this rapidly growing area according to the ...
Jian Luo   +4 more
openaire   +2 more sources

Revisiting the Passerini Reaction under Eco-Friendly Reaction Conditions

Synlett, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Carlos Kleber Z. Andrade   +3 more
openaire   +1 more source

Synthesis of Glycomimetics by Diastereoselective Passerini Reaction

The Journal of Organic Chemistry, 2018
We describe the utilization of bis-isopropylidene-protected d-fructose-derived aldehyde in the Passerini reaction with various acids and isocyanides. A library of densely functionalized glycomimetics bearing up to 3 carbohydrate units was obtained in high yields and diastereoselectivities.
Kristina Vlahoviček-Kahlina   +4 more
openaire   +3 more sources

Phosphoric Acid-Catalyzed Asymmetric Classic Passerini Reaction

Journal of the American Chemical Society, 2015
An efficient enantioselective classic three-component Passerini reaction with a broad substrate scope in the presence of a chiral phosphoric acid catalyst has been developed. This represents the general example for classic three-component Passerini reaction with good to excellent enantioselectivies involving aromatic aldehydes and the bulky ...
Jian, Zhang   +4 more
openaire   +2 more sources

Enediyne-Comprising Amino Aldehydes in the Passerini Reaction

ACS Combinatorial Science, 2018
Multicomponent reactions represent a highly efficient approach to a broad spectrum of structurally diverse compounds starting from simple and affordable compounds. A focused library of tweezers-like compounds is prepared by employing the multicomponent Passerini reaction comprising enediyne-derived amino aldehydes.
Mladena Glavaš   +2 more
openaire   +2 more sources

ChemInform Abstract: Solvent‐Free Passerini Reactions.

ChemInform, 2008
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Dominik Koszelewski   +3 more
openaire   +1 more source

Enzyme‐Promoted Asymmetric Tandem Passerini Reaction

ChemCatChem, 2017
AbstractA versatile and highly efficient three‐step, one‐pot, enzyme‐promoted Passerini tandem reaction has been developed. The chemoenzymatic sequence involved simultaneous enzyme catalyzed hydrolysis, subsequent Passerini reaction, and enzymatic kinetic resolution of the Passerini product.
Anna Żądło‐Dobrowolska   +5 more
openaire   +1 more source

ChemInform Abstract: Regioselective Passerini and Passerini—Knoevenagel Reactions with vic‐Diketo Amides.

ChemInform, 2014
AbstractVicinal diketo amides react with isonitriles and carboxylic acids to α‐acyloxy β‐keto carboxamides.
Jan Rossbach, Klaus Harms, Ulrich Koert
openaire   +1 more source

Regioselective Passerini and Passerini–Knoevenagel Reactions with vic‐Diketo Amides

European Journal of Organic Chemistry, 2013
AbstractThe Passerini reaction of vic‐diketo amides with a variety of isocyanides and carboxylic acids has been examined. α‐Acyloxy β‐keto carboxamides were formed regioselectively as the major products. For the Passerini reactions with electron‐withdrawing‐group‐substituted acetic acids, a one‐pot Passerini–Knoevenagel reaction was accomplished by the
Jan Roßbach, Klaus Harms, Ulrich Koert
openaire   +1 more source

Still Unconquered: Enantioselective Passerini and Ugi Multicomponent Reactions

Accounts of Chemical Research, 2018
The Passerini three-component (P-3CR) and the Ugi four-component (U-4CR) are two of the most prominent isocyanide-based multicomponent reactions (IMCRs). The P-3CR transforms isocyanides, aldehydes (ketones), and carboxylic acids to α-acyloxy carboxamides, while the U-4CR converts isocyanides, aldehydes (ketones), amines, and carboxylic acids to α ...
Qian Wang   +3 more
openaire   +2 more sources

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