Results 51 to 60 of about 6,650,580 (294)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Applied Sciences, 2017 This paper addresses three related issues concerning the path following control of a podded propulsion unmanned surface vehicle (USV), namely modeling, guidance and control.
Dongdong Mu +4 more
doaj +1 more source
Applied Sciences, 2020 This paper presents a novel robust control strategy for path following of an unmanned surface vehicle (USV) suffering from unknown dynamics and rudder saturation.
Bingbing Qiu, Guofeng Wang, Yunsheng Fan
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Progress report on the PATH Through Life Study [PDF]
, 2000 We finished interviewing people in their 20s in March this year, by which time we had interviewed 2404 people. Analysis of the 20-plus data is well under way. Our research team is currently preparing articles for scientific journals.
PATH Through Life Project
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Three-Dimensional Path-Following with Articulated 6DoF Robot and ToF Sensors
Applied SciencesThis paper presents an algorithm for 3D path-following using an articulated 6-Degree-of-Freedom (DoF) robot as well as experimental verification of the proposed approach.
Tymon F. Wawrzyniak +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
, 2021 The Journal Square Transportation Center is a multi-modal transportation hub located on Magnolia Avenue and Kennedy Boulevard[at Journal Square in Jersey City, .
Beards, Daniel E.
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