Results 91 to 100 of about 387,002 (288)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Systems understanding of plant—pathogen interactions through genome-wide protein—protein interaction networks [PDF]

Frontiers of Agricultural Science and Engineering, 2016
Plants are frequently affected by pathogen infections. To effectively defend against such infections, two major modes of innate immunity have evolved in plants; pathogen-associated molecular pattern-triggered immunity and effector-triggered immunity ...
Hong LI,Ziding ZHANG
doaj   +1 more source

Advances in Plant-Nematode Interactions with Emphasis on the Notorious Nematode Genus Meloidogyne. [PDF]

, 2019
Plant infections by plant-parasitic nematodes (PPNs) continue to be one of the major limitations in agricultural systems. Root-knot nematodes (RKNs), belonging to the genus Meloidogyne, are one of the most important groups of PPNs worldwide.
Kaloshian, Isgouhi, Teixeira, Marcella
core  

Bioaffinity detection of pathogens on surfaces [PDF]

, 2010
The demand for improved technologies capable of rapidly detecting pathogens with high sensitivity and selectivity in complex environments continues to be a significant challenge that helps drive the development of new analytical techniques. Surface-based
Faisal, S. N., Kim, S., Lee, H. J., Lee, J., Wark, Alastair   +4 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Receptor Mechanisms of the Inflammatory Process Initiation in Infectious Diseases

Zdorovʹe Rebenka, 2012
The review of scientific literature gives current ideas about the participation of the pattern-recognizing receptors in the induction of inflammatory reaction in response to the action of pathogen-associated molecular patterns of infectious pathogens.
Abaturov A.Ye. Abaturov A.Ye., Volosovets A.P. Volosovets A.P., Yulish Ye.I., Yulish Ye.I.,   +2 more
doaj   +1 more source

Brucella abortus ornithine lipids are dispensable outer membrane components devoid of a marked pathogen-associated molecular pattern. [PDF]

PLoS ONE, 2011
The brucellae are α-Proteobacteria facultative intracellular parasites that cause an important zoonosis. These bacteria escape early detection by innate immunity, an ability associated to the absence of marked pathogen-associated molecular patterns in ...
Leyre Palacios-Chaves, Raquel Conde-Álvarez, Yolanda Gil-Ramírez, Amaia Zúñiga-Ripa, Elías Barquero-Calvo, Carlos Chacón-Díaz, Esteban Chaves-Olarte, Vilma Arce-Gorvel, Jean-Pierre Gorvel, Edgardo Moreno, María-Jesús de Miguel, María-Jesús Grilló, Ignacio Moriyón, Maite Iriarte   +13 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1473-1493, June 2026.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Brucella infection and Toll-like receptors

Frontiers in Cellular and Infection Microbiology
Brucella consists of gram-negative bacteria that have the ability to invade and replicate in professional and non-professional phagocytes, and its prolonged persistence in the host leads to brucellosis, a serious zoonosis.
Hui Yu, Hui Yu, Xinyi Gu, Danfeng Wang, Zhanli Wang   +4 more
doaj   +1 more source

Innate Immune Recognition: An Issue More Complex Than Expected

Frontiers in Cellular and Infection Microbiology, 2019
Primary interaction of an intracellular bacterium with its host cell is initiated by activation of multiple signaling pathways in response to bacterium recognition itself or as cellular responses to stress induced by the bacterium.
Klara Kubelkova, Ales Macela
doaj   +1 more source