Results 41 to 50 of about 387,002 (288)
Non-canonical signalling mediates changes in fungal cell wall PAMPs that drive immune evasion
The authors show that the fungal pathogen Candida albicans exploits diverse host-associated signals, including specific nutrients and stresses, to promote immune evasion by masking cell wall β-glucan, a major pathogen-associated molecular pattern.
Arnab Pradhan +11 more
doaj +1 more source
Activation and regulation mechanisms of NOD-like receptors based on structural biology
Innate immunity is a primary defense system against microbial infections. Innate immune pattern recognition receptors (PRRs) play pivotal roles in detection of invading pathogens.
Umeharu Ohto
doaj +1 more source
Modulation of porcine intestinal epitheliocytes immunetranscriptome response by Lactobacillus jensenii TL2937 [PDF]
In order to evaluate probiotic strains applicable for the beneficial immunomodulation of the porcine gut (immunobiotics), we previously developed a porcine intestinal epitheliocyte cell line (PIE cells).
Albarracín, Leonardo Miguel +14 more
core +1 more source
Central Role for MyD88 in the Responses of Microglia to Pathogen-Associated Molecular Patterns [PDF]
Abstract Microglia, the innate immune effector cells of the CNS parenchyma, express TLR that recognize conserved motifs of microorganisms referred to as pathogen-associated molecular patterns (PAMP). All TLRs identified to date, with the exception of TLR3, use a common adaptor protein, MyD88, to transduce activation signals. Recently, we
Nilufer, Esen, Tammy, Kielian
openaire +2 more sources
In order to identify components of pathogen-associated molecular pattern–triggered immunity (PTI) pathways in Nicotiana benthamiana, we conducted a large-scale forward-genetics screen using virus-induced gene silencing and a cell-death-based assay for ...
Suma Chakravarthy +4 more
doaj +1 more source
Genome-wide analyses of Liberibacter species provides insights into evolution, phylogenetic relationships, and virulence factors. [PDF]
'Candidatus Liberibacter' species are insect-transmitted, phloem-limited α-Proteobacteria in the order of Rhizobiales. The citrus industry is facing significant challenges due to huanglongbing, associated with infection from 'Candidatus Liberibacter ...
Babcock B. +17 more
core +1 more source
Both plants and animals are endowed with sophisticated innate immune systems to combat microbial attack. In these multicellular eukaryotes, innate immunity implies the presence of cell surface receptors and intracellular receptors able to detect danger ...
Thibault Roudaire +7 more
doaj +1 more source
The Growing Threat of Agroterrorism and Strategies for Agricultural Defense [PDF]
Due to the dynamic nature of human conflict, non-traditional terror tactics have evolved to undermine the socioeconomic stability of targeted societies.
Forrest, Alyssa
core +1 more source
Germin and germin-like proteins: evolution, structure, and function [PDF]
Germin and germin-like proteins (GLPs) are encoded by a family of genes found in all plants. They are part of the cupin superfamily of biochemically diverse proteins, a superfamily that has a conserved tertiary structure, though with limited similarity ...
Dunwell, Jim +3 more
core +1 more source
DAMPs and Innate Immune Training
The ability to remember a previous encounter with pathogens was long thought to be a key feature of the adaptive immune system enabling the host to mount a faster, more specific and more effective immune response upon the reencounter, reducing the ...
Elisa Jentho +3 more
doaj +1 more source

