ADP-heptose is a newly identified pathogen-associated molecular pattern of <i>Shigella flexneri</i>. [PDF]
EMBO Rep, 2018 During an infection, the detection of pathogens is mediated through the interactions between pathogen-associated molecular patterns (PAMPs) and pathogen recognition receptors. β-Heptose 1,7-bisphosphate (βHBP), an intermediate of the lipopolysaccharide (LPS) biosynthesis pathway, was recently identified as a bacterial PAMP.
García-Weber D +7 more
europepmc +4 more sources
Eggplant and related species are promising genetic resources to dissect the plant immune response to Pseudomonas syringae and Xanthomonas euvesicatoria and to identify new resistance determinants [PDF]
, 2014 The apparent lack of durability of many resistance (R) genes highlights the need for the constant identification of new genetic sources of resistance for the breeding of new disease-resistant crop cultivars.
Clarke, Christopher R. +4 more
core +1 more source
Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines [PDF]
Trends in Biotechnology, 2011 Vaccine development has progressed significantly and has moved from whole microorganisms to subunit vaccines that contain only their antigenic proteins. Subunit vaccines are often less immunogenic than whole pathogens; therefore, adjuvants must amplify the immune response, ideally establishing both innate and adaptive immunity.
Stacey L, Demento +4 more
openaire +2 more sources
Chromatin-Associated Molecular Patterns (CAMPs) in sepsis
Cell Death and Disease, 2022 Several molecular patterns have been identified that recognize pattern recognition receptors. Pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) are commonly used terminologies to classify molecules ...
Colleen P. Nofi, Ping Wang, Monowar Aziz
doaj +1 more source
Phylogenetic congruence between subtropical trees and their associated fungi. [PDF]
, 2016 Recent studies have detected phylogenetic signals in pathogen-host networks for both soil-borne and leaf-infecting fungi, suggesting that pathogenic fungi may track or coevolve with their preferred hosts.
Etienne, Rampal S +4 more
core +3 more sources
Peripheral Neural Detection of Danger–Associated and Pathogen–Associated Molecular Patterns [PDF]
Critical Care Medicine, 2013 Bidirectional links between the nervous and immune systems modulate inflammation. The cellular mechanisms underlying the detection of danger-associated molecular patterns and pathogen-associated molecular patterns by the nervous system are not well understood.
Ackland, GL +4 more
openaire +4 more sources
Pathogenic Stress Induces Human Monocyte to Express an Extracellular Web of Tunneling Nanotubes
Frontiers in Immunology, 2021 Actin-based tunneling nanotubes are a means of intercellular communication between remote cells. In the last decade, this type of nanotube was described in a wide variety of cell types and it became widely accepted that communication through these ...
Michal Shahar, Auryan Szalat, Haim Rosen
doaj +1 more source
Nuclear processes associated with plant immunity and pathogen susceptibility [PDF]
, 2015 Plants are sessile organisms that have evolved exquisite and sophisticated mechanisms to adapt to their biotic and abiotic environment. Plants deploy receptors and vast signalling networks to detect, transmit and respond to a given biotic threat by ...
Huitema, Edgar +3 more
core +3 more sources
Suppression of CYP1 members of the AHR response by pathogen-associated molecular patterns [PDF]
Journal of Leukocyte Biology, 2017 AbstractThe aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that triggers a broad response, which includes the regulation of proinflammatory cytokine production by monocytes and macrophages. AHR is negatively regulated by a set of genes that it transcriptionally activates, including the AHR repressor (Ahrr) and the cytochrome
Adam G, Peres +3 more
openaire +2 more sources
Helicobacter pylori Pathogen-Associated Molecular Patterns: Friends or Foes?
International Journal of Molecular Sciences, 2022 Microbial infections are sensed by the host immune system by recognizing signature molecules called Pathogen-Associated Molecular Patterns—PAMPs. The binding of these biomolecules to innate immune receptors, called Pattern Recognition Receptors (PRRs), alerts the host cell, activating microbicidal and pro-inflammatory responses.
Eletto, Daniela +5 more
openaire +3 more sources