Results 251 to 260 of about 391,643 (293)

Pathogen-Associated Molecular Pattern in Cancer Immunotherapy

Critical Reviews™ in Immunology, 2008
Observations from different research frontiers--epidemiological data, case studies on spontaneous regressions from cancer, clinical studies, tumor immunology--indicate that exposure by vaccination or infection to pathogen-associated molecular patterns (PAMP) can have beneficial effects on neoplastic diseases, both prophylactically and therapeutically ...
Uwe, Hobohm, John L, Stanford, John M, Grange   +2 more
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Recognition of pathogen-associated molecular patterns by TLR family

Immunology Letters, 2003
Toll-like receptors (TLRs) are type I transmembrane proteins involved in innate immunity by recognizing microbial conserved structures. Recent studies have shown that TLR3 recognizes dsRNA, a viral product, whereas TLR9 recognizes unmethylated CpG motifs frequently found in the genome of bacteria and viruses, but not vertebrates.
Shizuo, Akira, Hiroaki, Hemmi
openaire   +2 more sources

Plant systems for recognition of pathogen-associated molecular patterns

Seminars in Cell & Developmental Biology, 2009
Research of the last decade has revealed that plant immunity consists of different layers of defense that have evolved by the co-evolutional battle of plants with its pathogens. Particular light has been shed on PAMP- (pathogen-associated molecular pattern) triggered immunity (PTI) mediated by pattern recognition receptors.
Sandra, Postel, Birgit, Kemmerling
openaire   +2 more sources

The effect of pathogen-associated molecular patterns on the swine granulosa cells

Theriogenology, 2020
Recent studies have demonstrated the surprising ability of reproductive endocrine cells to express receptors of innate immunity useful to sense danger in order to avoid disruption of tissue homeostasis. Present research demonstrates the presence of pattern recognition receptors, i.e. toll like receptors (TLR) TLR2, TLR4 and TLR 5 and NOD like receptors
Alessia Pacentra, Francesca Grasselli, Simona Bussolati, Stefano Grolli, Rosanna Di Lecce, Anna Maria Cantoni, Giuseppina Basini   +6 more
openaire   +3 more sources

The Roles of Pathogen-Associated Molecular Patterns in Atherosclerosis

Trends in Cardiovascular Medicine, 2008
Stimulation of Toll-like receptors, which serve to initiate inflammatory signaling in response to the detection of conserved microbial pathogen-associated molecular patterns (PAMPs), has been shown to play a central role in the development of atherosclerosis.
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Pathogen-Associated Molecular Patterns: The Synthesis of Heptose Phosphates and Derivatives

Synthesis, 2021
AbstractLipopolysaccharide biosynthesis metabolites, such as d-glycero-β-d-manno-heptopyranosyl 1,7-diphosphate, d-glycero-β-d-manno-heptopyranosyl phosphate, and adenosine 5′-(l-glycero-β-d-manno-heptopyranosyl)diphosphate, have been found to activate NF-κB via alpha-kinase 1 and TRAF-interacting protein with forkhead associated domain.
Janelle Sauvageau, Dean Williams, Mohammad P. Jamshidi   +2 more
openaire   +1 more source

Pathogen Associated Molecular Pattern Recognition in Innate Immunity

Ensho Saisei, 2003
Toll-like receptors (TLRs) play a critical role in the detection of invading pathogens and subsequent immune response against them. Individual TLRs recognize distinct microbial components. The TLR is a type 1 transmembrane receptor that is composed of an extracellular leucine-rich repeat (LRR) domain and cytoplasmic domain homologous to that of the IL ...
openaire   +1 more source

[Pathogen associated molecular patterns of parasite].

Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2014
With the research progress of classical pathogen associated molecular patterns (PAMPs) from pathogenic microbes, the presence of the parasite PAMPs has been confirmed. The parasite PAMPs show some differences from classical PAMPs in molecular structures, receptor binding ways, intracellular signal transduction pathways, and induced effects. This review
Qing-Li, Yang, Ji-Qing, Shen
openaire   +1 more source

Pathogen-Associated Molecular Patterns and Their Perception in Plants

2018
In plants, innate immunity, the first line of microbial recognition leading to active defense responses, relies on the perception of pathogen-associated molecular patterns (PAMPs) by pattern recognition receptors (PRRs). Pattern recognition receptors (PRRs) enable plants to sense non-self molecules exhibited by microbes and raise proper defense ...
Jitendra Singh Rathore, Chaitali Ghosh
openaire   +1 more source