Results 241 to 250 of about 633,152 (295)

Pattern recognition receptors in annelids

Developmental & Comparative Immunology, 2020
The existence of pattern recognition receptors (PRRs) on immune cells was discussed in 1989 by Charles Janeway, Jr., who proposed a general concept of the ability of PRRs to recognize and bind conserved molecular structures of microorganisms known as pathogen-associated molecular patterns (PAMPs).
Prochazkova, P., Roubalova, R., Dvorak, J., Navarro Pacheco, N.I., Bilej, M.   +4 more
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Pattern recognition receptors: an update

Expert Review of Clinical Immunology, 2006
The vertebrate immune system consists of two inter-related components, the innate and adaptive responses, which are required for the resolution of infection. The innate immune response is critical for the immediate protection from infection and for marshalling the B- and T-cell responses of the adaptive response.
Goutagny, Nadege, Fitzgerald, Katherine A   +1 more
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Pattern Recognition Receptors and Liver Failure

Critical Reviews in Immunology, 2019
Liver failure is a clinical syndrome with many causes, a complicated pathogenesis, diverse clinical manifestations, and very high mortality. No effective treatment is yet available. Main pathological processes of liver failure include direct damage to parenchymal and nonparenchymal liver cells that might be caused by viruses or drugs, immune-mediated ...
Wu, Jun, Han, Meihong, Li, Jia, Yang, Xiaoli, Zhen, Xin, Friedrich Schlaak, Joerg, Yang, Dongliang, Lu, Mengji   +7 more
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Antiviral Signaling Through Pattern Recognition Receptors

Journal of Biochemistry, 2006
Viral infection is detected by the host innate immune system. Innate immune cells such as dendritic cells and macrophages detect nucleic acids derived from viruses through pattern recognition receptors (PRRs). Viral recognition by PRRs initiates the activation of signaling pathways that lead to production of type I interferon and inflammatory cytokines,
Taro, Kawai, Shizuo, Akira
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Pattern recognition receptor function in neutrophils

Trends in Immunology, 2013
Previously, neutrophils were largely ignored in the pattern recognition receptor (PRR) signaling field. However, interest in neutrophil biology has been revitalized by emerging roles for neutrophils in promoting protective and pathogenic T helper (Th)17-driven immune responses and in orchestrating innate and adaptive immunity via cytokine/chemokine ...
Thomas, Christina J., Schroder, Kate
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Pattern-recognition Receptors in Pulp Defense

Advances in Dental Research, 2011
Initial sensing of infection is mediated by germline-encoded pattern-recognition receptors (PRRs), the activation of which leads to the expression of inflammatory mediators responsible for the elimination of pathogens and infected cells. PRRs act as immune sensors that provide immediate cell responses to pathogen invasion or tissue injury.
M-J, Staquet, F, Carrouel, J-F, Keller, C, Baudouin, P, Msika, F, Bleicher, T A, Kufer, J-C, Farges   +7 more
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Progresses on three pattern recognition receptor families (TLRs, RLRs and NLRs) in teleost.

Developmental and Comparative Immunology, 2021
Zhiwei Liao, Jianguo Su
semanticscholar   +1 more source

Pattern Recognition by Toll-like Receptors

2009
The mammalian immune system senses pathogens through pattern recognition receptors and responds with activation. The Toll-like receptors (TLRs) that are expressed on antigen presenting cells such as macrophages and dendritic cells play a critical role in this process.
Stefan, Bauer, Thomas, Müller, Svetlana, Hamm   +2 more
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CD14 Is a pattern recognition receptor

Immunity, 1994
Septic shock caused by a diverse group of bacterial pathogens is a serious human disease. Recognition of bacterial envelope constituents is one mechanism used by mammalian cells to initiate responses leading to bacterial killing or, unfortunately, responses that also cause fatal septic shock.
J, Pugin, I D, Heumann, A, Tomasz, V V, Kravchenko, Y, Akamatsu, M, Nishijima, M P, Glauser, P S, Tobias, R J, Ulevitch   +8 more
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WSA03 ‐ Pattern Recognition Receptors

European Journal of Immunology, 2009
AbstractNo ...
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