Results 141 to 150 of about 639,618 (274)

Updates on the Role of Innate Immunity's Pattern Recognition Receptors in Vitiligo Pathogenesis and Therapeutic Potential. [PDF]

Clin Cosmet Investig Dermatol
Feng J, Lu L, He H, Peng Y, Zhang S, Yang L, Liu Y, Wang T.   +7 more
europepmc   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

8-oxo-7,8-dihydroguanosine (8-oxo-Guo) drives pulmonary inflammatory pathways through pattern recognition receptors. [PDF]

Redox Biol
Li R, Pan JX, Sheng G, Gao XF, Huan R, Qi RM, Li J, Cai JP.   +7 more
europepmc   +1 more source

Convergent evolution of elicitin perception by divergent pattern-recognition receptors. [PDF]

Plant Cell, 2023
DeFalco TA.
europepmc   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Impact of Pattern Recognition Receptors on the Prognosis of Chemotherapy-treated Rectal Cancer Patients. [PDF]

In Vivo, 2023
Chang CL, Huang KC, Chen TW, Chen WT, Ke TW, Liou YF, Chao KSC, Chiang SF.   +7 more
europepmc   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Uncovering Convergent Pattern Recognition Receptors Recognising Phytophthora Across Plant Lineages. [PDF]

Plant Biotechnol J
Pei Y, Zhao Y, Wang H, Guo Y, Gu X, Lv J, Guo Z, Chen Y, Ren Y, Ren Y, Yan J, Wang Y, Ji P, Shen D, Yin Z, Dou D.   +15 more
europepmc   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

IL-10 Modulates the Expression and Activation of Pattern Recognition Receptors in Mast Cells. [PDF]

Int J Mol Sci, 2023
Riquelme-Neira R, Walker-Vergara R, Fernández-Blanco JA, Vergara P.   +3 more
europepmc   +1 more source