Results 151 to 160 of about 639,618 (274)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Targeting pattern recognition receptors for cancer therapy: Mechanisms and strategies. [PDF]

Acta Pharm Sin B
Ouyang D, Chen R, Xie H, Yang X, Li Q, Chen J.   +5 more
europepmc   +1 more source

Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus

Nature Immunology, 2000
E. Kurt-Jones, Lana Popova, Laura A. Kwinn, L. Haynes, L. Jones, R. Tripp, E. Walsh, M. Freeman, D. Golenbock, L. Anderson, R. Finberg   +10 more
semanticscholar   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Exploring the Role of Pattern Recognition Receptors as Immunostimulatory Molecules. [PDF]

Immun Inflamm Dis
Sharma M, Wagh P, Shinde T, Trimbake D, Tripathy AS.   +4 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Study on differentially expressed genes and pattern recognition receptors in osteoporosis based on bioinformatics analysis. [PDF]

Sci Rep
Mao S, Wang Y, Gu M, Liu K, Ma J, Miao J, Zhao F.   +6 more
europepmc   +1 more source

Corrigendum to: Pattern Recognition Receptors in Innate Immunity to Obligate Intracellular Bacteria. [PDF]

Zoonoses, 2023
Fisher JR, Chroust ZD, Onyoni F, Soong L.   +3 more
europepmc   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Nanocarrier-Based Targeting of Pattern Recognition Receptors as an Innovative Strategy for Enhancing Sepsis Therapy. [PDF]

Adv Healthc Mater
Ismail EA, Nyandoro VO, Omolo CA, Govender T.   +3 more
europepmc   +1 more source