Results 101 to 110 of about 861,453 (229)

An initial event in insect innate immune response: structural and biological studies of interactions between β-1,3-glucan and the N-terminal domain of β-1,3-glucan recognition protein [PDF]

, 2013
In response to invading microorganisms, insect β-1,3-glucan recognition protein (βGRP), a soluble receptor in the hemolymph, binds to the surfaces of bacteria and fungi and activates serine protease cascades that promote destruction of pathogens by means
Amzel L. M., An C., Barral P., Boraston A. B., Brünger A. T., Buchon N., Cavanagh C., Clore G. M., Cornilescu G., Daisuke Takahashi, David VanderVelde, Delaglio F., Deslandes Y., Fabrick J. A., Fabrick J. A., Goddard T. D., Gottar M., Handa N., Hiromasa Y., Hiromasa Y., Hrmova M., Huaien Dai, Jeffrey A. Fabrick, Jiang H., Kanagawa M., Kim Y. S., Laughton A. M., Lim J. H., Ma C., Matskevich A. A., Michael R. Kanost, Mishima Y., Ochiai M., Okuyama K., Peng J. W., Perkins S. J., Ramaswamy Krishnamoorthi, Roh K. B., Schachman H. K., Takahasi K., Wang Y., Weis W. I., Wiseman T., Wishart D. S., Yasuaki Hiromasa, Young S. H.   +45 more
core   +2 more sources

Editorial: Pattern Recognition Receptors and Cancer

Frontiers in Immunology, 2015
The problem of cancer remains one of the most immense challenges to current biomedical research. Affecting populations in all countries and all regions, this disease is responsible for millions of deaths annually (1). Evasion of the immune system is an ominous feature of cancers, which often leads to tumor outgrowth, epithelial–mesenchymal transition ...
Kutikhin, Anton G., Yuzhalin, Arseniy E.
openaire   +2 more sources

Pattern Recognition Receptors: From the Cell Surface to Intracellular Dynamics

Molecular Plant-Microbe Interactions, 2007
Detection of potentially infectious microorganisms is essential for plant immunity. Microbial communities growing on plant surfaces are constantly monitored according to their conserved microbe-associated molecular patterns (MAMPs).
Denise Altenbach, Silke Robatzek
doaj   +1 more source

Phosphorylation is required for the pathogen defense function of the Arabidopsis PEN3 ABC transporter. [PDF]

, 2017
The Arabidopsis PEN3 ABC transporter accumulates at sites of pathogen detection, where it is involved in defense against a number of pathogens. Perception of PAMPs by pattern recognition receptors initiates recruitment of PEN3 and also leads to PEN3 ...
Somerville, Shauna, Underwood, William
core   +1 more source

Ligand-induced endocytosis of the pattern recognition receptor FLS2 in Arabidopsis.

Genes & Development, 2006
Pattern-recognition receptors (PRRs) trigger innate immune responses in animals and plants. One such PRR is the flagellin receptor FLS2 in Arabidopsis. Here, we demonstrate that a functional fusion of FLS2 to the green fluorescent protein (GFP) resides ...
S. Robatzek, D. Chinchilla, T. Boller
semanticscholar   +1 more source

Type I interferon and pattern recognition receptor signaling following particulate matter inhalation

Particle and Fibre Toxicology, 2012
Background Welding, a process that generates an aerosol containing gases and metal-rich particulates, induces adverse physiological effects including inflammation, immunosuppression and cardiovascular dysfunction.
Erdely Aaron, Antonini James M, Salmen-Muniz Rebecca, Liston Angie, Hulderman Tracy, Simeonova Petia P, Kashon Michael L, Li Shengqiao, Gu Ja K, Stone Samuel, Chen Bean T, Frazer David G, Zeidler-Erdely Patti C   +12 more
doaj   +1 more source

ER-mediated control for abundance, quality, and signaling of transmembrane immune receptors in plants

Frontiers in Plant Science, 2014
Plants recognize a wide range of microbes with cell-surface and intracellular immune receptors. Transmembrane pattern recognition receptors (PRRs) initiate immune responses upon recognition of cognate ligands characteristic of microbes or aberrant ...
Nico eTintor, Yusuke eSaijo
doaj   +1 more source

Virus perception at the cell surface: revisiting the roles of receptor‐like kinases as viral pattern recognition receptors

Molecular plant pathology, 2019
Summary Activation of antiviral innate immune responses depends on the recognition of viral components or viral effectors by host receptors. This virus recognition system can activate two layers of host defence, pathogen‐associated molecular pattern ...
R. M. Teixeira, Marco Aurélio Ferreira, Gabriel A. S. Raimundo, V. Loriato, P. A. Reis, E. Fontes   +5 more
semanticscholar   +1 more source

Receptor-Like Cytoplasmic Kinases Directly Link Diverse Pattern Recognition Receptors to the Activation of Mitogen-Activated Protein Kinase Cascades in Arabidopsis[OPEN]

The Plant Cell, 2018
Multiple pattern-recognition receptors activate mitogen-activated protein kinase cascades and trigger disease resistance in plants via direct phosphorylation and positive feedback regulation.
Guozhi Bi, Zhaoyang Zhou, Weibing Wang, Lin Li, Shaofei Rao, Ying Wu, Xiaojuan Zhang, Frank L. H. Menke, She Chen, Jian‐Min Zhou   +9 more
semanticscholar   +1 more source

Role of toll-like receptors in pulmonary immunity: mechanisms and therapeutic implications

Frontiers in Immunology
Toll-like receptors (TLRs) belong to the family of pattern recognition receptors (PRRs), playing critical roles in linking innate with adaptive immunity by recognizing pathogen-associated molecular patterns (PAMPs) and danger-associated molecular ...
Zhuojian Qu, Zhiliang Guo, Chunjuan Yang, Xiumei Guan, Min Cheng, Pingping Wang, Donghua Xu, Donghua Xu   +7 more
doaj   +1 more source