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Pattern Recognition by Toll-like Receptors
2009The mammalian immune system senses pathogens through pattern recognition receptors and responds with activation. The Toll-like receptors (TLRs) that are expressed on antigen presenting cells such as macrophages and dendritic cells play a critical role in this process.
Stefan, Bauer +2 more
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Pattern Recognition Receptors in Plant Immunity
Plant innate immunity is an advanced defense system to counteract pathogenic stresses. It relies on the recognition of microbial invasion through cell surface-localized pattern recognition receptors (PRRs) and intracellular nucleotide-binding domain leucine-rich repeat receptors (NLRs).Mughair, Abdul Aziz +2 more
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Pattern Recognition by NOD-Like Receptors
Nucleotide-binding oligomerization domain-like receptors (NLRs) are a family of cytosolic pattern recognition receptors (PRRs) and able to respond to conserved microbe-associated molecular patterns (MAMPs) and endogenous damage-associated molecular patterns (DAMPs).Timo-Daniel, Voss +2 more
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Therapeutic targeting of pattern-recognition receptors
International Immunopharmacology, 2006Innate immune system could recognize the pathogen-associated molecular patterns by pattern-recognition receptors like Toll-like receptor (TLR) and nucleotide-binding oligomerisation domain (NOD) protein. Information regarding the structure and signalling pathways of TLRs and NODs could provide opportunities for new therapeutic approaches to modulate ...
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Autophagy and Pattern Recognition Receptors
2016Autophagy is an evolutionarily conserved eukaryotic process that eliminates intracellular components through lysosomal degradation for recycling. It is a hierarchized multistep process that is involved in a multitude of cellular functions and its fine regulation is required for cell homeostasis as indicated by the various pathologies associated with ...
Christophe Viret, Mathias Faure
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Pattern Recognition Receptor Antagonism
Science Signaling, 2014A pathogenic fungus activates two C-type lectin receptors to skew the T cell response to one favorable to infection.
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WSA03 ‐ Pattern Recognition Receptors
European Journal of Immunology, 2009AbstractNo ...
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Pattern Recognition Receptors and Aging
2013Pattern recognition receptors (PRRs), such as the toll-like receptors (TLRs), C-type lectin receptors (CLRs), nucleotide-binding oligomerization domain and leucine-rich repeat-containing receptors (NLRs), and the more recently discovered cytosolic RNA- and DNA-sensing receptors, are a crucial element of the innate immune system owing to their function ...
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