Results 141 to 150 of about 10,828 (178)
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PAX8 Expression in Breast Cancer
Applied Immunohistochemistry & Molecular Morphology, 2020PAX8 expression is frequently detected in renal, thyroidal, and Müllerian carcinomas, and PAX8 immunohistochemistry is often used to confirm the origin of these tumors. Tumors metastatic to the breast may masquerade as primary breast lesions. PAX8 is strongly expressed in tumors of Müllerian origin and largely negative in breast primaries, but an ...
Shaolei, Lu +4 more
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Diagnostic roles of PAX8 immunohistochemistry in ovarian tumors
Pathology Research and Practice, 2023This study aimed to elucidate the diagnostic roles of PAX8 immunohistochemistry in various ovarian tumors.We searched through the PubMed database and selected the eligible studies to perform the meta-analysis. The PAX8 immunohistochemical expression rates of various ovarian tumors, including primary and metastatic carcinomas, were analyzed. In addition,
Nae Yu Kim, Dong Wook Kang
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NordiQC Assessments of PAX8 Immunoassays
Applied Immunohistochemistry & Molecular Morphology, 2018This paper is number 3 in a series developed through a partnership between ISIMM and NordiQC for the purpose of reporting research assessing the performance characteristics of immunoassays in an external proficiency testing program.
Røge, Rasmus +4 more
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PAX8, an Emerging Player in Ovarian Cancer
2021Ovarian Cancer is one of the most lethal and widespread gynecological malignancies. It is the seventh leading cause of all cancer deaths worldwide. High-Grade Serous Cancer (HGSC), the most commonly occurring subtype, alone contributes to 70% of all ovarian cancer deaths.
Gokulnath P +4 more
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F329L polymorphism in the human PAX8 gene
American Journal of Medical Genetics, 1997We screened patients with juvenile nephronophthisis for mutations of the tightly linked PAX8 gene. No disease-associated mutations were found, but we identified the first known human PAX8 polymorphism, F329L, in 1 of 15 patients and 2 of 20 controls. This polymorphic variant involves a conservative amino acid change (phenylalanine to leucine) in the C ...
E, Torban, J, Pelletier, P, Goodyer
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The Diagnostic Utility of PAX8 for Neuroendocrine Tumors
Applied Immunohistochemistry & Molecular Morphology, 2016PAX8 is a transcription factor crucial for the development of the kidneys, thyroid glands, and Mullerian system. It is commonly expressed by epithelial tumors from these organs. Recently, the diagnostic utility of PAX8 has been expanded to pancreatic neuroendocrine tumors (NETs). However, PAX8 is not expressed by pancreatic islets during organogenesis.
Jau-Yu, Liau +6 more
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SLEEP, 2023
Abstract Introduction The biological basis of daytime sleepiness and excessive sleep duration in patients with unexplained hypersomnolence is unknown. However, a growing body of evidence suggests modulations in the epigenome coincide with objective measures of sleep, suggesting epigenetic mechanisms ...
Andy Madrid +7 more
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Abstract Introduction The biological basis of daytime sleepiness and excessive sleep duration in patients with unexplained hypersomnolence is unknown. However, a growing body of evidence suggests modulations in the epigenome coincide with objective measures of sleep, suggesting epigenetic mechanisms ...
Andy Madrid +7 more
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Pax8 Expression in Thymic Epithelial Neoplasms
American Journal of Surgical Pathology, 2011Pax8 is a transcription factor associated with the embryonic development of the thyroid gland, kidney, and the Müllerian system and plays a role in the tumorigenesis of these organs. Pax8 has been shown to be expressed immunohistochemically in a high percentage of tumors of thyroid, renal, and Müllerian origin in both primary and metastatic sites.
Annikka, Weissferdt, Cesar A, Moran
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PAX2 and PAX8: Useful Markers for Metastatic Effusions
Acta Cytologica, 2013<b><i>Objective:</i></b> It was the aim of this study to determine the utility of PAX2 and PAX8 in cytology effusions with metastatic tumor. <b><i>Study Design:</i></b> PAX2 and PAX8 immunohistochemical staining was performed on cell blocks of 89 pleural, pericardial and peritoneal effusions with benign ...
Lindsay, Waters +4 more
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PAX8 (Paired Box Protein PAX8)
2009PAX8 (Paired Box Protein PAX8) The paired box (PAX) genes code for a family of transcription factors containing a paired box domain, an octapeptide, and a paired-type homeodomain. PAX proteins are essential for the formation of several tissues from all germ layers in the mammalian embryo.
DE BIASE, DARIO +2 more
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