Results 61 to 70 of about 10,828 (178)

Age related neoplasm in experimental animals [PDF]

open access: yesIraqi Journal of Veterinary Sciences
The albino rats are commonly recognized as tumor-resistant and appreciable research interest because of the scarcity of reports and article papers on neoplasm tumors.
Hadil B. Al-Sabaawy
doaj   +1 more source

Expression Landscape and Circadian Regulation of lncRNAs in the Kidney

open access: yesActa Physiologica, Volume 242, Issue 8, August 2026.
ABSTRACT Recent multi‐omics work shows that the diurnal rhythmicity of kidney function is associated with circadian oscillations in renal mRNA, protein and metabolite abundances. Yet circadian regulation of renal lncRNAs, which are emerging as important modulators of diverse (patho)physiological processes, remains largely unexplored. Here, we provide a
Leonore Wigger   +4 more
wiley   +1 more source

Evolving Pathology of Anaplastic Thyroid Carcinoma: Integrating Morphology, Immunohistochemistry, and Molecular Insights

open access: yesCancer Science, Volume 117, Issue 8, Page 2029-2039, August 2026.
Schematic overview of progression from differentiated thyroid carcinoma (DTC) to anaplastic thyroid carcinoma (ATC). ATC primarily develops via two pathways: the BRAF p.V600E‐mutated papillary thyroid carcinoma (PTC) pathway and the RAS‐mutated pathway. The origin and progression of BRAF/RAS‐wildtype ATC remain unclear.
Toru Odate, Tetsuo Kondo
wiley   +1 more source

Molecular Characterization of Ovarian Yolk Sac Tumor in a Postmenopausal Woman: Implications for Pathogenesis

open access: yesJournal of Obstetrics and Gynaecology Research, Volume 52, Issue 8, August 2026.
ABSTRACT Ovarian yolk sac tumor is a rare malignant germ cell tumor that typically occurs in young women. In postmenopausal women, yolk sac tumors are extremely rare and have a poor prognosis. These tumors may arise from different biological mechanisms, as germ cells are absent in postmenopausal ovaries.
Mihiro Dejima   +5 more
wiley   +1 more source

Diagnostic Challenges in Choroid Plexus Tumours

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
In this review, we summarise the diagnostic spectrum of choroid plexus tumours, highlight key age‐dependent differential diagnoses across infants, children/adolescents and adults, and outline how histopathology, immunohistochemistry and molecular profiling support accurate tumour classification.
Christian Thomas, Martin Hasselblatt
wiley   +1 more source

A WT1-positive pleural neoplasm. Is it always a mesothelioma?

open access: yesAfrican Journal of Thoracic and Critical Care Medicine, 2023
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G Gaggero, D Taietti, M Concardi, M Mora
doaj  

Novel non-synonymous mutations of PAX8 in a cohort of Chinese with congenital hypothyroidism

open access: yesChinese Medical Journal, 2019
. Background:. The transcription factor paired box 8 (PAX8) was associated with type 2 congenital non-goitrous hypothyroidism (CHNG2), a clinical phenotype of congenital hypothyroidism (CH). Though studied in a few regions with different ethnicities, the
Fang Qian   +7 more
doaj   +1 more source

Diagnostic utility of PAX8 in differentiation of mullerian from non-mullerian tumors

open access: yesAdvanced Biomedical Research, 2014
Background: Considering the high prevalence of female genital tract neoplasms, non-specific nature of the initial symptoms, higher possibility of metastasis by the time of diagnosis, importance of differentiating metastatic Mullerian tumors or metastatic
Mitra Heidarpour, Zahra Tavanafar
doaj   +1 more source

Diagnostic algorithm for determining primary tumor sites using peritoneal fluid.

open access: yesPLoS ONE, 2018
This study was conducted to develop a novel algorithm for determining the origin of tumors by combining analysis of cluster patterns with immunocytochemistry (ICC) for markers in cells from fine-needle aspirates of ascites.
Cheol Keun Park   +2 more
doaj   +1 more source

Comparative genomics reveals a functional thyroid-specific element in the far upstream region of the PAX8 gene

open access: yesBMC Genomics, 2010
Background The molecular mechanisms leading to a fully differentiated thyrocite are still object of intense study even if it is well known that thyroglobulin, thyroperoxidase, NIS and TSHr are the marker genes of thyroid differentiation.
De Felice Mario   +7 more
doaj   +1 more source

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