Global Sensitivity Analysis of a Physiologically-based Pharmacokinetic (PBPK) Model of Bromochloromethane [PDF]
, 2020 Sawyer, Colton
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In Silico Dosimetry Study of Tc99m-Tetrofosmin in Children Using a Novel PBPK Model in Humans Built from SPECT Imaging Data. [PDF]
Pharm Res, 2023 Kaikousidis C, Dokoumetzidis A.
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Development, testing, parameterisation, and calibration of a human PBPK model for the plasticiser, di-(2-ethylhexyl) terephthalate (DEHTP) using in silico, in vitro and human biomonitoring data. [PDF]
Front Pharmacol, 2023 McNally K, Sams C, Hogg A, Loizou G.
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Using available in vitro metabolite identification and time course kinetics for β-chloroprene and its metabolite, (1-chloroethenyl) oxirane, to include reactive oxidative metabolites and glutathione depletion in a PBPK model for β-chloroprene. [PDF]
Front Pharmacol, 2023 Campbell JL +4 more
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Cluster Gauss-Newton method analyses of PBPK model parameter combinations of coproporphyrin-I based on OATP1B-mediated rifampicin interaction studies. [PDF]
CPT Pharmacometrics Syst Pharmacol, 2022 Yoshikado T +6 more
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This deliverable will report the final development of the human PBPK models developed within ...
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A PBPK model recapitulates early kinetics of anti-PEG antibody-mediated clearance of PEG-liposomes. [PDF]
J Control Release, 2022 Talkington AM +10 more
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Modeling and Simulation of Triclosan Kinetics and Distribution in Humans Using a PBPK Model [PDF]
, 2015 Andreassen, Monica +5 more
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Optimization of Bottom-Up PBPK Model Development in SIMCYP via Retrospective Analysis of Clinical Human PK Data. [PDF]
Clin Transl SciSchulz Pauly JA +7 more
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Predicting Regional Respiratory Tissue and Systemic Concentrations of Orally Inhaled Drugs through a Novel PBPK Model. [PDF]
Drug Metab Dispos, 2022 Ladumor MK, Unadkat JD.
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