Results 171 to 180 of about 12,486 (248)

A physiologically based pharmacokinetic (PBPK) model to describe organ distribution of ⁶⁸Ga-DOTATATE in patients without neuroendocrine tumors. [PDF]

EJNMMI Res, 2021
Siebinga H, de Wit-van der Veen BJ, Beijnen JH, Stokkel MPM, Dorlo TPC, Huitema ADR, Hendrikx JJMA.   +6 more
europepmc   +1 more source

Evaluation of Adefovir PBPK Model to Assess Biomarker-Informed OAT1 Drug-Drug Interaction and Effect of Chronic Kidney Disease. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tan SPF, Wu H, Rostami-Hodjegan A, Scotcher D, Galetin A.   +4 more
europepmc   +1 more source

Development of PBPK model for intra-articular injection in human: methotrexate solution and rheumatoid arthritis case study. [PDF]

J Pharmacokinet Pharmacodyn, 2021
Le Merdy M, Mullin J, Lukacova V.
europepmc   +1 more source

stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments. [PDF]

Front Pharmacol
Visintainer R, Fochesato A, Boaretti D, Giampiccolo S, Watson S, Levi M, Reali F, Marchetti L.   +7 more
europepmc   +1 more source

Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends. [PDF]

Front Pharmacol, 2021
Abouir K, Samer CF, Gloor Y, Desmeules JA, Daali Y.   +4 more
europepmc   +1 more source

A Parent-Metabolite Middle-Out PBPK Model for Genistein and Its Glucuronide Metabolite in Rats: Integrating Liver and Enteric Metabolism with Hepatobiliary and Enteroluminal Transport to Assess Glucuronide Recycling. [PDF]

Pharmaceutics
Ramisetty BS, Singh R, Hu M, Wang MZ.
europepmc   +1 more source

Addressing Adherence Using Genotype-Specific PBPK Modeling—Impact of Drug Holidays on Tamoxifen and Endoxifen Plasma Levels [PDF]

, 2017
Georg Hempel, Kristin J. R. Dickschen, Michael Block, Stefan Willmann   +3 more
core   +1 more source

Development of a Physiologically Based Pharmacokinetic (PBPK) Model for F-53B in Pregnant Mice and Its Extrapolation to Humans. [PDF]

Environ Sci Technol
Zhang J, Li SP, Li QQ, Zhang YT, Dong GH, Canchola A, Zeng X, Chou WC.   +7 more
europepmc   +1 more source

Author Correction: A comprehensive physiologically based pharmacokinetic (PBPK) model for nicotine in humans from using nicotine-containing products with different routes of exposure. [PDF]

Sci Rep, 2022
Rostami AA, Campbell JL, Pithawalla YB, Pourhashem H, Muhammad-Kah RS, Sarkar MA, Liu J, McKinney WJ, Gentry R, Gogova M.   +9 more
europepmc   +1 more source

Recent Progress on Physiologically Based Pharmacokinetic (PBPK) Model: A Review Based on Bibliometrics. [PDF]

Toxics
Huang H, Zhao W, Qin N, Duan X.
europepmc   +1 more source