Results 181 to 190 of about 12,447 (257)

Evaluation of Adefovir PBPK Model to Assess Biomarker-Informed OAT1 Drug-Drug Interaction and Effect of Chronic Kidney Disease. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tan SPF, Wu H, Rostami-Hodjegan A, Scotcher D, Galetin A.   +4 more
europepmc   +1 more source

A comprehensive physiologically based pharmacokinetic (PBPK) model for nicotine in humans from using nicotine-containing products with different routes of exposure. [PDF]

Sci Rep, 2022
Rostami AA, Campbell JL, Pithawalla YB, Pourhashem H, Muhammad-Kah RS, Sarkar MA, Liu J, McKinney WJ, Gentry R, Gogova M.   +9 more
europepmc   +1 more source

stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments. [PDF]

Front Pharmacol
Visintainer R, Fochesato A, Boaretti D, Giampiccolo S, Watson S, Levi M, Reali F, Marchetti L.   +7 more
europepmc   +1 more source

Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends. [PDF]

Front Pharmacol, 2021
Abouir K, Samer CF, Gloor Y, Desmeules JA, Daali Y.   +4 more
europepmc   +1 more source

A Parent-Metabolite Middle-Out PBPK Model for Genistein and Its Glucuronide Metabolite in Rats: Integrating Liver and Enteric Metabolism with Hepatobiliary and Enteroluminal Transport to Assess Glucuronide Recycling. [PDF]

Pharmaceutics
Ramisetty BS, Singh R, Hu M, Wang MZ.
europepmc   +1 more source

Development of a Physiologically Based Pharmacokinetic (PBPK) Model for F-53B in Pregnant Mice and Its Extrapolation to Humans. [PDF]

Environ Sci Technol
Zhang J, Li SP, Li QQ, Zhang YT, Dong GH, Canchola A, Zeng X, Chou WC.   +7 more
europepmc   +1 more source

Recent Progress on Physiologically Based Pharmacokinetic (PBPK) Model: A Review Based on Bibliometrics. [PDF]

Toxics
Huang H, Zhao W, Qin N, Duan X.
europepmc   +1 more source

Model-Informed Radiopharmaceutical Therapy Optimization: A Study on the Impact of PBPK Model Parameters on Physical, Biological, and Statistical Measures in ¹⁷⁷Lu-PSMA Therapy. [PDF]

Cancers (Basel)
Abdollahi H, Fele-Paranj A, Rahmim A.
europepmc   +1 more source

Can 3D Printed Tablets Be Bioequivalent and How to Test It: A PBPK Model Based Virtual Bioequivalence Study for Ropinirole Modified Release Tablets. [PDF]

Pharmaceutics
Shuklinova O, Wyszogrodzka-Gaweł G, Baran E, Lisowski B, Wiśniowska B, Dorożyński P, Kulinowski P, Polak S.   +7 more
europepmc   +1 more source

PBPK model reporting template for chemical risk assessment applications. [PDF]

Regul Toxicol Pharmacol, 2020
Tan YM, Chan M, Chukwudebe A, Domoradzki J, Fisher J, Hack CE, Hinderliter P, Hirasawa K, Leonard J, Lumen A, Paini A, Qian H, Ruiz P, Wambaugh J, Zhang F, Embry M.   +15 more
europepmc   +1 more source