Results 151 to 160 of about 2,075,986 (324)

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

ECtHR-PCR: A Dataset for Precedent Understanding and Prior Case Retrieval in the European Court of Human Rights [PDF]

arXiv
In common law jurisdictions, legal practitioners rely on precedents to construct arguments, in line with the doctrine of \emph{stare decisis}. As the number of cases grow over the years, prior case retrieval (PCR) has garnered significant attention. Besides lacking real-world scale, existing PCR datasets do not simulate a realistic setting, because ...
arxiv  

PCr RECOVERY RATES IN MUSCLE OF OLD VS. ADULT RATS

, 1985
Ronald A. Meyer, Truman R. Brown, Gary A. Dudley   +2 more
openalex   +1 more source

Prevalence of human papillomavirus types 16 and 18 in penile carcinoma: a study of 41 cases using PCR. [PDF]

, 1994
Kwok Wah Chan, Alfred K. Lam, Alexander C.L. Chan, Patrick Lau, Gopesh Srivastava   +4 more
openalex   +1 more source

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

Molecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen, Chung‐Teng Wang, Jia‐Ming Chang, Ai‐Li Shiau, Gia‐Shing Shieh, Yau‐Lin Tseng, Yi‐Ting Yen, Tang‐Hsiu Huang, Li‐Hsin Cheng, Yu‐Chih Wu, Chao‐Liang Wu, Bing‐Hua Su, Pensee Wu   +12 more
wiley   +1 more source

Corrigendum to “Extraction of HCV-RNA from Plasma Samples: Development towards Semiautomation”

International Journal of Analytical Chemistry, 2016
Imran Amin, Tania Jabbar, Fawad Ali, Muhammad Saeed Akhtar   +3 more
doaj   +1 more source

Molecular Epidemiology of Hepatitis B Virus in Turkish Cypriot [PDF]

Polish Journal of Microbiology, 2019
UNAL SUMER, MURAT SAYAN
doaj   +1 more source

Identification and relatedness of coronatine-producing Pseudomonas syringae pathovars by PCR analysis and sequence determination of the amplification products [PDF]

, 1994
Stefan Bereswill, Peter Bugert, Beate Völksch, Matthias S. Ullrich, Carol L. Bender, Klaus Geider   +5 more
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Application of PCR to a clinical and environmental investigation of a case of equine botulism [PDF]

, 1994
Éva Szabó, John Pemberton, Angela M. Gibson, Rosa Thomas, R. R. Pascoe, Patricia Desmarchelier   +5 more
openalex   +1 more source