Results 31 to 40 of about 4,063 (166)

C-Reactive Protein and Cancer: Interpreting the Differential Bioactivities of Its Pentameric and Monomeric, Modified Isoforms

Frontiers in Immunology, 2021
C-reactive protein (CRP) was first recognized in the 1940s as a protein that appeared in blood during acute episodes of infectious disease. Its presence and pharmacodynamics were found in essentially all diseases that involved tissue damage and ...
Lawrence A. Potempa, Ibraheem M. Rajab, Margaret E. Olson, Peter C. Hart   +3 more
doaj   +1 more source

The Teatro Nacional Popular and Peruvian Cultural Policy (1973-1978) [PDF]

, 1991
SK Pengabdian Durian Batubusuk Genap 2018 ...
Slawson, Richard J.
core   +3 more sources

Transposon and deletion mutagenesis of genes involved in perchlorate reduction in Azospira suillum PS. [PDF]

, 2013
UnlabelledAlthough much work on the biochemistry of the key enzymes of bacterial perchlorate reduction, chlorite dismutase, and perchlorate reductase has been published, understanding of the molecular mechanisms of this metabolism has been somewhat ...
Clark, Iain C, Coates, John D, Liao, Annette, Melnyk, Ryan A   +3 more
core   +2 more sources

Factor H-Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation [PDF]

, 2015
The physiological roles of the factor H (FH)-related proteins are controversial and poorly understood. Based on genetic studies, FH-related protein 5 (CFHR5) is implicated in glomerular diseases, such as atypical hemolytic uremic syndrome, dense deposit
Banlaki, Z, Caesar, JJE, Csincsi, AI, Daigo, K, de Jorge, EG, Hamakubo, T, Hebecker, M, Jozsi, M, Kopp, A, Lea, SM, Pickering, MC, Uzonyi, B, Zoeldi, M   +12 more
core   +3 more sources

Pentameric C-reactive protein is a better prognostic biomarker and remains elevated for longer than monomeric CRP in hospitalized patients with COVID-19

Frontiers in Immunology, 2023
The differing roles of the pentameric (p) and monomeric (m) C-reactive protein (CRP) isoforms in viral diseases are not fully understood, which was apparent during the COVID-19 pandemic regarding the clinical course of severe acute respiratory syndrome ...
Francis R. Hopkins, Johan Nordgren, Rafael Fernandez-Botran, Helena Enocsson, Melissa Govender, Cecilia Svanberg, Lennart Svensson, Lennart Svensson, Marie Hagbom, Åsa Nilsdotter-Augustinsson, Åsa Nilsdotter-Augustinsson, Sofia Nyström, Sofia Nyström, Christopher Sjöwall, Johanna Sjöwall, Johanna Sjöwall, Marie Larsson   +16 more
doaj   +1 more source

A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury

Frontiers in Immunology, 2018
IntroductionC-reactive protein circulates as a pentameric protein (pCRP). pCRP is a well-established diagnostic marker as plasma levels rise in response to tissue injury and inflammation.
Jan R. Thiele, Johannes Zeller, Jurij Kiefer, David Braig, Sheena Kreuzaler, Yvonne Lenz, Lawrence A. Potempa, Florian Grahammer, Florian Grahammer, Tobias B. Huber, Tobias B. Huber, Tobias B. Huber, M. Huber-Lang, Holger Bannasch, G. Björn Stark, Karlheinz Peter, Steffen U. Eisenhardt   +16 more
doaj   +1 more source

mCRP as a Biomarker of Adult-Onset Still’s Disease: Quantification of mCRP by ELISA

Frontiers in Immunology, 2022
BackgroundC-reactive protein (CRP) is a dynamic protein that undergoes conformational changes between circulating native pentameric CRP (pCRP), pentameric symmetrical forms (pCRP*) and monomeric (or modified) CRP (mCRP) forms.
Chitose Fujita, Chitose Fujita, Yasuo Sakurai, Yasuo Sakurai, Yuki Yasuda, Rino Homma, Cheng-Long Huang, Cheng-Long Huang, Masaaki Fujita, Masaaki Fujita, Masaaki Fujita, Masaaki Fujita   +11 more
doaj   +1 more source

CRP Is Transported by Monocytes and Monocyte-Derived Exosomes in the Blood of Patients with Coronary Artery Disease

Biomedicines, 2020
The objective of this work was to study the ability of blood cells and their microparticles to transport monomeric and pentameric forms of C-reactive protein (mCRP and pCRP) in the blood of patients with coronary artery disease (CAD).
Ivan Melnikov, Sergey Kozlov, Olga Saburova, Ekaterina Zubkova, Olga Guseva, Sergey Domogatsky, Tatiana Arefieva, Natalia Radyukhina, Maria Zvereva, Yuliya Avtaeva, Lyudmila Buryachkovskaya, Zufar Gabbasov   +11 more
doaj   +1 more source

Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes

Frontiers in Immunology, 2018
C-reactive protein (CRP) is a member of the pentraxin superfamily that is widely recognized as a marker of inflammatory reactions and cardiovascular risk in humans.
James D. McFadyen, James D. McFadyen, James D. McFadyen, Jurij Kiefer, David Braig, Julia Loseff-Silver, Lawrence A. Potempa, Steffen Ulrich Eisenhardt, Karlheinz Peter, Karlheinz Peter, Karlheinz Peter   +10 more
doaj   +1 more source

Covering Pairs in Directed Acyclic Graphs† [PDF]

, 2016
The Minimum Path Cover (MinPC) problem on directed acyclic graphs (DAGs) is a classical problem in graph theory that provides a clear and simple mathematical formulation for several applications in computational biology.
Beerenwinkel, Niko, Beretta, Stefano, Bonizzoni, Paola, Dondi, Riccardo, Pirola, Yuri   +4 more
core   +2 more sources