Results 41 to 50 of about 2,447 (150)

Predicting prostate cancer recurrence: Introducing PCRPS, an advanced online web server

open access: yesHeliyon
Prostate cancer (PCa) is one of the leading causes of cancer death in men. About 30% of PCa will develop a biochemical recurrence (BCR) following initial treatment, which significantly contributes to prostate cancer-related deaths. In clinical practice, accurate prediction of PCa recurrence is crucial for making informed treatment decisions.
Xianya He   +8 more
openaire   +3 more sources

The ‘Prostate Cancer Screening for People at Genetic Risk of Aggressive Disease’ (PATROL) study

open access: yesBJU International, Volume 138, Issue 4, Page 600-606, October 2026.
Background Inherited (germline) pathogenic and likely pathogenic variants (gPVs) in key genes associated with increased risk of prostate cancer (PCa) now warrant more attentive PCa screening per National Comprehensive Cancer Network (NCCN) guidelines—e.g., BRCA2, HOXB13, ATM, BRCA1, MSH2, MSH6, CHEK2 and TP53.
Heather H. Cheng   +12 more
wiley   +1 more source

Three Essays in Applied Microeconomics [PDF]

open access: yes, 2018
This thesis focuses on three vulnerable groups in Europe that have recently been highlighted both in media and in the economics literature; and that are policy priorities. Chapter 1 is a joint work with Giovanni Mastrobuoni which focuses on prisoners and
Rialland, PCRP
core   +5 more sources

The binding of monomeric C-reactive protein (mCRP) to Integrins αvβ3 and α4β1 is related to its pro-inflammatory action.

open access: yesPLoS ONE, 2014
The prototypic acute phase reactant C-reactive protein (CRP) is not only a marker but also a potential contributor to inflammatory diseases. CRP exists as the circulating native, pentameric CRP (pCRP) and the monomeric isoform (mCRP), formed as a result ...
Masaaki Fujita   +3 more
doaj   +1 more source

A Review of Anti-C Reactive Protein Antibodies in Systemic Lupus Erythematosus

open access: yesJournal of Interdisciplinary Medicine, 2021
Systemic lupus erythematosus (SLE), the prototype autoimmune disease, is characterized by the production of a plethora of autoantibodies with various roles in the development of disease-related tissue damage.
Richter Patricia   +5 more
doaj   +1 more source

Systemic Propagation of STING Signalling via Generation of Large Extracellular Vesicles

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Large extracellular vesicles (EVs) derived from tumour cells play important roles in tumour formation and progression. However, it remains unclear why malignant cells produce these EVs and how they act in vivo. We employ a well‐characterized Drosophila tumour model and demonstrate that large EV biogenesis from malignant cells is an ...
Jiae Lee   +3 more
wiley   +1 more source

Docking simulation predicts that mCRP binds to integrin αvβ3 but pCRP does not.

open access: yes, 2014
a) The headpiece of integrin αvβ3 (PDB code 1LG5) was used as a target. The docking model predicts that mCRP (red) binds to the RGD-binding site of the integrin αvβ3 headpiece (green and blue). Amino acid residues involved in αvβ3-mCRP interaction are in
Yoko K. Takada (365353)   +3 more
core   +1 more source

Reimagining the “Well” (Digitally) Literate Body: Lessons From Children's Diverse (Digital)‐Literacies‐in‐the‐Body With Videogames at Home

open access: yesReading Research Quarterly, Volume 61, Issue 2, April/May/June 2026.
This graphical abstract provides an overview of the study's context, approach, key findings and implications. This ecoculturally informed study examined children's digital play and well‐being in relation to broader contexts, routines and practices.
Fiona Scott   +5 more
wiley   +1 more source

mCRP specifically binds to αvβ3, but pCRP less efficiently binds to the integrin.

open access: yes, 2014
Wells of 96 well microtiter plate were coated with mCRP or pCRP and remaining protein-binding sites were blocked with BSA. a) ELISA-type integrin binding assay.
Yoko K. Takada (365353)   +3 more
core   +1 more source

Effect of aerobic exercise combined with saffron extract supplementation on serum levels of tumor necrosis factor-α and C-reactive protein in rats following an aerobic exercise until exhaustion

open access: yesComplementary Medicine Journal of Faculty of Nursing and Midwifery, 2022
Objective: Aerobic exercise and Saffron has beneficial effects on inflammatory response. The present study aims to investigate the effect of aerobic exercise combined with saffron extract supplementation on serum levels of Tumor Necrosis Factor-α (TNF-α)
Amir Khosravi   +3 more
doaj  

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