Results 21 to 30 of about 2,499 (154)
The binding of monomeric C-reactive protein (mCRP) to Integrins αvβ3 and α4β1 is related to its pro-inflammatory action. [PDF]
PLoS ONE, 2014 The prototypic acute phase reactant C-reactive protein (CRP) is not only a marker but also a potential contributor to inflammatory diseases. CRP exists as the circulating native, pentameric CRP (pCRP) and the monomeric isoform (mCRP), formed as a result ...
Masaaki Fujita +3 more
doaj +2 more sources
Coupling Efficiency of a Partially Coherent Radially Polarized Vortex Beam into a Single-Mode Fiber
Applied Sciences, 2018 We study the problem of coupling partially coherent radially polarized (PCRP) vortex beams into a single-mode optical fiber. Using the well-known concept of the cross-spectral density (CSD) matrix, we derive a general expression for the coupling ...
Xinlei Zhu +4 more
doaj +2 more sources
Mood Disorder Begins in the Mouth: Periodontitis Mediates Anxiety-Like Behaviors. [PDF]
Adv Sci (Weinh)ABSTRACT The previous study elucidated that the C‐reactive protein (CRP)/bone morphogenetic protein 4 (BMP4) signaling pathway mediates periodontitis‐associated anxiety‐like behaviors in rats. This molecular crosstalk along the periodontal‐hippocampal axis provides novel insights into the etiology and mechanisms of emotional disorders. However, several
Chen Z, Li X.
europepmc +2 more sources
Pancreatic cancer-related pain: mechanism and management
Journal of Pancreatology, 2023 Pancreatic cancer-related pain (PCRP) gains widespread attention for its high prevalence, extreme complexity, poor prognosis, and decreased survival rate. Current treatment of PCRP remains unsatisfactory since the underlying mechanism is not clear.
Meijing Wu, Afang Zhu, Le Shen
doaj +1 more source
, 2022 Application of STENCIL in the PCRP was an NIH-initiated project to screen 800 antibodies in ChIP-exo. NIH project requirements included providing the generated data in a community-accessible manner.
Prashant K. Kuntala (12066243) +5 more
core +2 more sources
Arthritis Research & Therapy, 2022 Background Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a large production of autoantibodies and deficient clearance of cellular waste.
Jesper Karlsson +5 more
doaj +1 more source
Frontiers in Immunology, 2023 C-reactive protein (CRP) is an acute phase, predominantly hepatically synthesized protein, secreted in response to cytokine signaling at sites of tissue injury or infection with the physiological function of acute pro-inflammatory response. Historically,
Margaret E. Olson +8 more
doaj +1 more source
C-Reactive Protein in Atherosclerosis—More than a Biomarker, but not Just a Culprit
Reviews in Cardiovascular Medicine, 2023 C-reactive protein (CRP) is a pentraxin that is mainly synthesized in the liver in response to inflammatory cytokines. It exists in two functionally and structurally distinct isoforms.
Kürsat Kirkgöz
doaj +1 more source
A ChIP-exo screen of 887 PCRP transcription factor antibodies in human cells [PDF]
, 2020 Abstract Antibodies offer a powerful means to interrogate specific proteins in a complex milieu. However, antibody availability and reliability are problematic and epitope tagging can be impractical in many cases. In an effort to improve this situation, the Protein Capture Reagents Program (PCRP) generated over a ...
William K. M. Lai +24 more
openaire +1 more source
Frontiers in Immunology, 2021 C-reactive protein (CRP) was first recognized in the 1940s as a protein that appeared in blood during acute episodes of infectious disease. Its presence and pharmacodynamics were found in essentially all diseases that involved tissue damage and ...
Lawrence A. Potempa +3 more
doaj +1 more source