Monomeric CRP is Elevated in Patients with COPD Compared to Non-COPD Control Persons
Journal of Inflammation Research, 2021 Revathy Munuswamy,1,* Jana De Brandt,2,* Chris Burtin,2 Wim Derave,3 Joseph Aumann,4 Martijn A Spruit,5,6,* Luc Michiels1,* 1Faculty of Medicine and Life Sciences, Biomedical Research Institute BIOMED, Hasselt University, Hasselt, Belgium;
Luc Michiels +2 more
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In vitro generation and bioactivity evaluation of C-reactive protein intermediate. [PDF]
PLoS ONE, 2018 The conformational conversion of pentameric C-reactive protein (pCRP) to monomeric CRP (mCRP) has been shown to play important roles in the action of CRP in inflammation regulation.
Jian-Min Lv, Ming-Yu Wang
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C-Reactive Protein in Atherosclerosis—More than a Biomarker, but not Just a Culprit
Reviews in Cardiovascular Medicine, 2023 C-reactive protein (CRP) is a pentraxin that is mainly synthesized in the liver in response to inflammatory cytokines. It exists in two functionally and structurally distinct isoforms.
Kürsat Kirkgöz
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Dissociation of C-Reactive Protein Localizes and Amplifies Inflammation: Evidence for a Direct Biological Role of C-Reactive Protein and Its Conformational Changes [PDF]
Frontiers in Immunology, 2018 C-reactive protein (CRP) is a member of the pentraxin superfamily that is widely recognized as a marker of inflammatory reactions and cardiovascular risk in humans.
James D. McFadyen +10 more
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Arthritis Research & Therapy, 2022 Background Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by a large production of autoantibodies and deficient clearance of cellular waste.
Jesper Karlsson +5 more
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C-reactive protein in cardiovascular disease: clinical associations, conformation-dependent biology, and therapeutic perspectives [PDF]
Frontiers in ImmunologyC-reactive protein (CRP) is a widely used biomarker of systemic inflammation and cardiovascular risk. Its clinical and experimental relevance has been investigated across major cardiovascular disease (CVD) phenotypes, including coronary artery disease ...
Bingxing Gong +8 more
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A Conformational Change in C-Reactive Protein Enhances Leukocyte Recruitment and Reactive Oxygen Species Generation in Ischemia/Reperfusion Injury [PDF]
Frontiers in Immunology, 2018 IntroductionC-reactive protein circulates as a pentameric protein (pCRP). pCRP is a well-established diagnostic marker as plasma levels rise in response to tissue injury and inflammation.
Jan R. Thiele +16 more
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Factors Associated with Referral of Patients with Advanced Cancer Utilizing a Palliative Care Referral Protocol [PDF]
Revista Brasileira de CancerologiaIntroduction: Numerous barriers hinder timely referral to palliative care (PC) leading to inadequate symptom management and diminished quality of life.
Bianca Sakamoto Ribeiro Paiva +4 more
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The Effects of a Mindfulness-Based Intervention on Depression and Anxiety in the Long-COVID Population [PDF]
Journal of Patient-Centered Research and ReviewsLong-COVID is a complicated, post-viral syndrome involving multiple body systems and can present with neuropsychiatric symptoms. Little has been reported about the neuropsychiatric symptoms of long-COVID, and validated treatments do not yet exist.
Rachel Welbel +4 more
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A conformational change of C-reactive protein drives neutrophil extracellular trap formation in inflammation [PDF]
BMC BiologyBackground C-reactive protein (CRP) represents a routine diagnostic marker of inflammation. Dissociation of native pentameric CRP (pCRP) into the monomeric structure (mCRP) liberates proinflammatory features, presumably contributing to excessive immune ...
Ebru Karasu +17 more
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