Results 61 to 70 of about 2,447 (150)
The Role of Anti-mCRP Autoantibodies in Lupus Nephritis
Background: Lupus nephritis is characterized by multiple autoantibodies production. However, there are few autoantibodies associated with disease activity and prognosis.
Mo Yuan, Ying Tan, Ming-hui Zhao
doaj +1 more source
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon +7 more
wiley +1 more source
Biochemically prepared C-reactive protein conformational states differentially affect C1q binding
C-reactive protein (CRP) is commonly measured as an inflammatory marker in patient studies for coronary heart disease, autoimmune disease and recent acute infections.
Carrie L. Moon +4 more
doaj +1 more source
Defeating lethal cancer: Interrupting the ecologic and evolutionary basis of death from malignancy
Abstract Despite the advances in cancer prevention, early detection, and treatments, all of which have led to improved cancer survival, globally, there is an increased incidence in cancer‐related deaths. Although each patient and each tumor is wholly unique, the tipping point to incurable disease is common across all patients: the dual capacity for ...
Kenneth J. Pienta +2 more
wiley +1 more source
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang +10 more
wiley +1 more source
Coupling Efficiency of a Partially Coherent Radially Polarized Vortex Beam into a Single-Mode Fiber
We study the problem of coupling partially coherent radially polarized (PCRP) vortex beams into a single-mode optical fiber. Using the well-known concept of the cross-spectral density (CSD) matrix, we derive a general expression for the coupling ...
Xinlei Zhu +4 more
doaj +1 more source
ABSTRACT Background An unmet clinical need requires the discovery of new treatments for men facing advanced prostate cancer. Aberrant glycosylation is a universal feature of cancer cells and plays a key role in tumour growth, immune evasion and metastasis.
Kayla Bastian +28 more
wiley +1 more source
ABSTRACT Introduction C‐reactive protein (CRP) is an inflammatory biomarker, implicated in the pathogenesis of atherosclerotic lesion formation, plaque rupture, and coronary thrombosis. The relationship between preprocedural CRP levels and subsequent development of in‐stent restenosis (ISR) after percutaneous coronary intervention (PCI) however remains
Himanshu Rai +6 more
wiley +1 more source
Abstract Background Radiomics‐based characterization of fluid and retinal tissue compartments of spectral‐domain optical coherence tomography (SD‐OCT) scans has shown promise to predict anti‐VEGF therapy treatment response in diabetic macular edema (DME). Radiomics features are sensitive to different image acquisition parameters of OCT scanners such as
Sudeshna Sil Kar +4 more
wiley +1 more source
The surface-induced intermediate exhibited enhanced complement interaction capacity.
5 μg/ml pCRP or mCRP was immobilized in TBS-Ca or TBS-EDTA (pH 7.4) at 4°C overnight. Alternatively, 50 μg/ml pCRP was bound to immobilized PC-BSA overnight at 4°C in TBS-Ca (pH 7.4).
Jian-Min Lv (5324774) +1 more
core +1 more source

