Results 51 to 60 of about 4,063 (166)

A Review of Anti-C Reactive Protein Antibodies in Systemic Lupus Erythematosus

Journal of Interdisciplinary Medicine, 2021
Systemic lupus erythematosus (SLE), the prototype autoimmune disease, is characterized by the production of a plethora of autoantibodies with various roles in the development of disease-related tissue damage.
Richter Patricia, Burlui Alexandra, Bratoiu Ioana, Cardoneanu Anca, Rezus Ciprian, Rezus Elena   +5 more
doaj   +1 more source

The primordial binary population II: Recovering the binary population for intermediate mass stars in Sco OB2

, 2007
We characterize the binary population in the young and nearby OB association Scorpius OB2 using available observations of visual, spectroscopic, and astrometric binaries with intermediate-mass primaries.
A. G. A. Brown, Alencar, Andersen, Bahcall, Balega, Barbier-Brossat, Basri, Bate, Bertiau, Blaauw, Blaauw, Bouy, Brown, Brown, Buscombe, Chabrier, Chanamé, Chen, Close, Correia, Cruzalebes, de Bruijne, de Geus, de Zeeuw, Duflot, Duquennoy, Eggleton, Evans, Fryer, Fryer, Girardi, Gualandris, Hanson, Hartkopf, Heacox, Heacox, Heggie, Hillebrandt, Hills, Hoogerwerf, Hut, Jilinski, Jordi, Kouwenhoven, Kouwenhoven, Kraicheva, Kraus, Kraus, Kroupa, Kroupa, Kroupa, Kroupa, Kurosawa, L. Kaper, Levato, Lindegren, Lindroos, M. B. N. Kouwenhoven, Malkov, Mamajek, Mason, Mason, Mathieu, Mathis, McAlister, Meibom, Meynet, Miura, Oblak, Palla, Perryman, Perryman, Plummer, Portegies Zwart, Portegies Zwart, Preibisch, Preibisch, Preibisch, Robin, S. F. Portegies Zwart, Shatsky, Slesnick, Slettebak, Sowell, Svechnikov, Söderhjelm, Thackeray, Tokovinin, Tokovinin, van Albada, van den Heuvel, Vereshchagin, Verschueren, Worley, Worley, Yungelson   +95 more
core   +1 more source

Evaluation of Marine Boundary Layer Clouds Over the Northeast Pacific During the CSET Campaign in E3SM Version 2

Journal of Geophysical Research: Atmospheres, Volume 130, Issue 19, 16 October 2025.
Abstract It is still challenging to reproduce marine boundary layer (MBL) clouds well in large‐scale models despite their importance to the Earth's radiation budget and hydrological cycle. This study evaluates representation of the MBL and clouds in the Energy Exascale Earth System Model (E3SM) version 2. This study compares the E3SM simulation results
Kyoung Ock Choi, Philip J. Rasch, Robert Wood, Sarah J. Doherty, Hui Wan, Hailong Wang, Shixuan Zhang, Kai Zhang, Mingxuan Wu   +8 more
wiley   +1 more source

The binding of monomeric C-reactive protein (mCRP) to Integrins αvβ3 and α4β1 is related to its pro-inflammatory action.

PLoS ONE, 2014
The prototypic acute phase reactant C-reactive protein (CRP) is not only a marker but also a potential contributor to inflammatory diseases. CRP exists as the circulating native, pentameric CRP (pCRP) and the monomeric isoform (mCRP), formed as a result ...
Masaaki Fujita, Yoko K Takada, Yoshihiro Izumiya, Yoshikazu Takada   +3 more
doaj   +1 more source

Natural selection and genetic variation in a promising Chagas disease drug target: Trypanosoma cruzi trans-sialidase [PDF]

, 2017
Rational drug design is a powerful method in which new and innovative therapeutics can be designed based on knowledge of the biological target aiming to provide more efficacious and responsible therapeutics.
Gallant, Joseph P.
core   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science, Volume 12, Issue 38, October 13, 2025.
Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie de Avila, Mei‐Jun Zhu, Min Du   +9 more
wiley   +1 more source

Effect of aerobic exercise combined with saffron extract supplementation on serum levels of tumor necrosis factor-α and C-reactive protein in rats following an aerobic exercise until exhaustion

Complementary Medicine Journal of Faculty of Nursing and Midwifery, 2022
Objective: Aerobic exercise and Saffron has beneficial effects on inflammatory response. The present study aims to investigate the effect of aerobic exercise combined with saffron extract supplementation on serum levels of Tumor Necrosis Factor-α (TNF-α)
Amir Khosravi, Parisa Khosravi, Saeed Daneshyar, Vahid Valipour Dehnou   +3 more
doaj  

KDM4 Orchestrates Epigenomic Remodeling of Senescent Cells and Potentiates the Senescence‐Associated Secretory Phenotype

Aging Cell, Volume 24, Issue 10, October 2025.
The chromatin accessibility landscape of senescent cells is remodeled, with a set of activated transcription factors physically binding to the enhancers and promoters of senescence‐associated genes, including those encoding SASP factors. Events such as epigenomic reprogramming and KDM4‐mediated histone demethylation (H3K9/H3K36) enable SASP expression ...
Boyi Zhang, Qilai Long, Shanshan Wu, Qixia Xu, Shuling Song, Liu Han, Min Qian, Xiaohui Ren, Hanxin Liu, Jing Jiang, Jianming Guo, Xiaoling Zhang, Xing Chang, Qiang Fu, Eric W.‐F. Lam, Judith Campisi, James L. Kirkland, Yu Sun   +17 more
wiley   +1 more source

Extracellular vesicles are associated with C-reactive protein in sepsis

Scientific Reports, 2021
There is increasing evidence that C-reactive protein (CRP) can mediate inflammatory reactions following the transformation of functionally inert pentameric CRP (pCRP) into its structural isoform pCRP* and into monomeric CRP (mCRP).
Birgit Fendl, René Weiss, Tanja Eichhorn, Ingrid Linsberger, Taras Afonyushkin, Florian Puhm, Christoph J. Binder, Michael B. Fischer, Viktoria Weber   +8 more
doaj   +1 more source

Proton beam therapy in the management of skull base chordomas: systematic review of indications, outcomes, and implications for neurosurgeons [PDF]

, 2016
BACKGROUND: Chordomas are rare tumours affecting the skull base. There is currently no clear consensus on the post-surgical radiation treatments that should be used after maximal tumour resection.
Choi, D, Matloob, SA, Nasir, HA
core   +1 more source