Results 1 to 10 of about 638,166 (167)

Molecular dynamics insights into the redox effects on PD-1/PD-L1 and PD-1/PD-L2 interactions [PDF]

Scientific Reports
The PD-1/PD-L1/PD-L2 immune checkpoint plays a critical role in regulating immune responses, and its dysfunction is implicated in immune evasion by cancer cells.
Rasulbek Mashalov, Zulfizar Toshpulatova, Zhitong Chen, Jamoliddin Razzokov   +3 more
doaj   +2 more sources

Anti‐PD‐1/PD‐L1 Immunotherapy as a Potential Treatment Option for Lung Cancer: A Perspective Analysis of Opportunities and Challenges [PDF]

Health Science Reports
Background and Aims Anti‐PD‐1/PD‐L1 immunotherapy has changed the treatment landscape of lung cancer. This new approach provides the ability to revitalize the immune system to specifically target and kill cancer cells, thereby creating a new treatment ...
Md Mohiuddin
doaj   +2 more sources

The PD‐1 Interactome [PDF]

Advanced Biology, 2021
AbstractT cell activation is a fine‐tuned process that involves T cell receptor and costimulation signals. To prevent undue activation of T cells, inhibitory molecules including PD‐1 (programmed death 1) are induced and function as brakes for T cell signaling.
Qi Wang, Kankana Bardhan, Vassiliki A. Boussiotis, Nikolaos Patsoukis   +3 more
openaire   +2 more sources

نقش PD-1/ PD-L1 و Anti-PD-1/ PD-L1 در پیشرفت و سرکوب سرطان [PDF]

Majallah-i Dānishkadah-i Pizishkī-i Dānishgāh-i ̒ Ulūm-i Pizishkī-i Mashhad., 2023
نقاط کنترل ایمنی (Immune checkpoints) مجموعه ای از گیرنده های تنظیمی می باشند که باعث کنترل پاسخ های ایمنی، حفظ تولرانس و هموستاز می شود. سلول های توموری می توانند با به خدمت گرفتن این نقاط از دسترس پاسخ های اختصاصی ضد تومورال بگریزند و گسترش پیدا کنند ...
نرگس عبدالهی, محمود محمودی, آمنه رئوف رحمتی, سید علیرضا اسماعیلی   +3 more
doaj   +1 more source

Towards European Transitions: Indicators for the Development of Marginal Urban Regions

Land, 2022
Urban transitions and urban-scape have been heavily impacted by the COVID-19 pandemic and will likely be affected by the current Ukrainian-Russian conflict.
Rubina Canesi, Giuliano Marella
doaj   +1 more source

Research at the University of Padova in the Field of Space Debris Impacts against Satellites: An Overview of Activities in the Last 10 Years

Applied Sciences, 2023
Space debris represent a threat to satellites in orbit around Earth. In the case of impact, satellites can be subjected to damage spanning from localized craterization to subsystem failure, to complete loss of the vehicle; large collision events may lead
Lorenzo Olivieri, Cinzia Giacomuzzo, Stefano Lopresti, Alessandro Francesconi   +3 more
doaj   +1 more source

Recognition of Additive Manufacturing Parts Based on Neural Networks and Synthetic Training Data: A Generalized End-to-End Workflow

Applied Sciences, 2023
Additive manufacturing (AM) is becoming increasingly relevant among established manufacturing processes. AM parts must often be recognized to sort them for part- or order-specific post-processing.
Jonas Conrad, Simon Rodriguez, Daniel Omidvarkarjan, Julian Ferchow, Mirko Meboldt   +4 more
doaj   +1 more source

Effect of platelet rich plasma in non surgically treated chronic Achilles tendon ruptures

Foot & Ankle Surgery: Techniques, Reports & Cases, 2023
Background: Achille's tendon ruptures are relatively common among foot and ankle injuries. They are considered chronic when last beyond 4-6 weeks from the time of injuries.
Paolo Lorenzon, MD, Enrico Scalco, MD, Michele Scomazzon, MD   +2 more
doaj   +1 more source

Relationships between Biomarkers of Oxidative Stress in Seminal Plasma and Sperm Motility in Bulls before and after Cryopreservation

Animals, 2022
This study aimed at evaluating the relationship between biomarkers of oxidative stress (OS) in seminal plasma and sperm motility in bulls before and after cryopreservation. Three ejaculates per bull were collected from 20 young bulls.
Veronica Vigolo, Elisa Giaretta, Laura Da Dalt, Jana Damiani, Gianfranco Gabai, Federica Bertuzzo, Maria Elena Falomo   +6 more
doaj   +1 more source

Tumor Infiltrating Lymphocyte Expression of PD-1 Predicts Response to Anti-PD-1/PD-L1 Immunotherapy [PDF]

Journal of Immunotherapy and Precision Oncology, 2022
Introduction: Many studies have focused on the role of programmed death receptor ligand 1 (PD-L1) expression in predicting immunotherapy outcomes. Limited clinical data are available regarding the role of programmed death receptor 1 (PD-1; the PD-L1 ...
Nicholas J. Bevins, Ryosuke Okamura, Meagan Montesion, Jacob J. Adashek, Aaron M. Goodman, Razelle Kurzrock   +5 more
doaj   +1 more source