Results 101 to 110 of about 54,977 (304)

Clinical characteristics of the PDAC patients.

, 2012
Clinical characteristics of the PDAC patients.
Godefridus J. Peters (121184), Arjan van der Velde (121156), Niccola Funel (121159), Elisa Giovannetti (121153), Hiroko Sudo (121176), Enrico Vasile (121161), Valentina Gallá (121175), Vittorio Perrone (121164), Leticia G. Leon (121166), Luca E. Pollina (121173), Nelide De Lio (121168), Ugo Boggi (121182), Amir Avan (121170), Daniela Campani (121180), Sara Caponi (121172), Alfredo Falcone (121178)   +15 more
core   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Blockade of CC chemokine receptor 2 suppresses pancreatic cancer progression through the interaction with macrophages in the tumor microenvironment

Scientific Reports
Pancreatic ductal adenocarcinoma (PDAC) is the most intractable cancer, demonstrating abundant stroma in the tumor microenvironment (TME). Previously, we reported that CXC chemokines contributed to the progression of PDAC through tumor-stromal ...
Gen Kimura, Hideaki Ijichi, Makoto Sano, Genso Notoya, Koji Miyabayashi, Ryota Takahashi, Takahiro Kishikawa, Mitsuhiro Fujishiro   +7 more
doaj   +1 more source

Characteristics of CP and PDAC patients.

, 2014
Characteristics of CP and PDAC patients.
Holger Kalthoff (243490), Christian Röder (180601), Hans-Heinrich Oberg (559363), Domantas Petrick (559360), Dieter Kabelitz (468539), Ole Helm (559358), Ruben Mennrich (559359), Daniela Wesch (559364), Sandra Freitag-Wolf (449419), Heiner Schäfer (559362), Christoph Röcken (170345), Susanne Sebens (559365), Lisa Goebel (559361), Bence Sipos (161263)   +13 more
core   +1 more source

Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy

Advanced Science, EarlyView.
A timeline of the research history of 3D biomimetic scaffold materials and platforms. With advances in biomimetic materials and 3D scaffold technologies, their functional scope has expanded from mimicking basic physical and biochemical properties to increasingly replicating complex pathophysiological processes.
Haitao Zhao, Yuechen Han, Jie Li, Peng Luo, Lin Qi, Zhiwei Xia, Xiaosong Li, Quan Cheng, Chenshen Huang, Wantao Wu, Hao Zhang   +10 more
wiley   +1 more source

The role of autophagy-inactivated acinar cell in PDAC initiation

, 2022
International audienceDespite the extensive research on PDAC and the development of various late stage-PDAC models, the 5-years survival rate of patients is below 5% (1).
Shalhoub, Hala, Ramos-Delgado, Fernanda, Dufresne, Marlene, Guyon, Camille, Guillermet-Guibert, Julie, Boutet-Robinet, Elisa, Joffre, Carine, Thibault, Benoit   +7 more
core   +2 more sources

Transcriptome-wide association study and Mendelian randomization in pancreatic cancer identifies susceptibility genes and causal relationships with type 2 diabetes and venous thromboembolismResearch in context

EBioMedicine
Summary: Background: Two important questions regarding the genetics of pancreatic adenocarcinoma (PDAC) are 1. Which germline genetic variants influence the incidence of this cancer; and 2.
Marcus C.B. Tan, Chelsea A. Isom, Yangzi Liu, David-Alexandre Trégouët, Lang Wu, Dan Zhou, Eric R. Gamazon, Sara Lindstrom, Lu Wang, Erin Smith, William Gordon, Astrid Van Hylckama Vlieg, Mariza De Andrade, Jennifer Brody, Jack Pattee, Jeffrey Haessler, Ben Brumpton, Daniel Chasman, Pierre Suchon, Ming-Huei Chen, Constance Turman, Marine Germain, Kerri Wiggins, James MacDonald, Sigrid Braekkan, Sebastian Armasu, Nathan Pankratz, Rabecca Jackson, Jonas Nielsen, Franco Giulianini, Marja Puurunen, Manal Ibrahim, Susan Heckbert, Theo Bammler, Kelly Frazer, Bryan McCauley, Kent Taylor, James Pankow, Alexander Reiner, Maiken Gabrielsen, Jean-François Deleuze, Chris O'Donnell, Jihye Kim, Barbara McKnight, Peter Kraft, John-Bjarne Hansen, Frits Rosendaal, John Heit, Bruce Psaty, Weihong Tang, Charles Kooperberg, Kristian Hveem, Paul Ridker, Pierre-Emmanuel Morange, Andrew Johnson, Christopher Kabrhel, David-Alexandre Trégouët, Nicholas Smith   +57 more
doaj   +1 more source

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki, Norio Kubo, Yuhei Miyasaka, Hayato Ikota, Ryo Muranushi, Mariko Tsukagoshi, Takamichi Igarashi, Masahiko Okamoto, Tatsuya Ohno, Ken Shirabe   +9 more
wiley   +1 more source

The dynamic contrast-enhanced curves in hypo-PNETs and PDAC.

, 2019
The CT attenuation of hypo-PNETs and PDAC was 33.4 ± 4.9 and 34.0 ± 5.2 Hounsfield units at the unenhanced CT images, respectively.
Shuai Ren (6288722), Zhongqiu Wang (283253), Zhonglan Wang (6288725), Jianhua Wang (159545), Xiao Chen (260187), Rui Zhao (43391), Wenjing Cui (296467)   +6 more
core   +1 more source

Achievement of the Ideal Outcome After Pancreatectomy for Pancreatic Ductal Adenocarcinoma Is Associated With Earlier Initiation and Higher Completion Rates of Adjuvant Chemotherapy and Improved Long‐Term Survival

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background The Ideal Outcome is a composite quality indicator reflecting optimal postoperative course after pancreatic surgery. This study aimed to clarify the prognostic significance of achieving the Ideal Outcome and its influence on the initiation and completion of adjuvant chemotherapy.
Ryosuke Fukushima, Kenichiro Araki, Ryo Muranushi, Kouki Hoshino, Kei Hagiwara, Shunsuke Kawai, Mariko Tsukagoshi, Takamichi Igarashi, Norio Kubo, Ken Shirabe   +9 more
wiley   +1 more source