The pyruvate dehydrogenase complex in concert with the DNA/RNA-binding protein YBX1 regulates cell senescence and tumorigenesis. [PDF]
Chen H +12 more
europepmc +1 more source
PLK1-mediated PDHA1 phosphorylation drives mitochondrial dysfunction, mitophagy, and cancer progression in Cr(VI)-associated lung cancer. [PDF]
Zhang Q +16 more
europepmc +1 more source
Integrated phenotypic and proteomic screening identifies top-tier Alzheimer's disease therapeutic targets. [PDF]
Cary GA +12 more
europepmc +1 more source
Genetically encoded manipulation of ATP/ADP ratio in human cells uncovers proteomic and physiological signatures of energy stress. [PDF]
Ekvik AE, Kober MM, Titov DV.
europepmc +1 more source
Targeting cuproptosis for treatment and prognostic assessment in endometrial cancer. [PDF]
Yu J +5 more
europepmc +1 more source
Congenital vs adult-onset estrogen deficiency in female mice: physiological effects and implications for therapy. [PDF]
Aladhami AK +10 more
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The enzymatic mechanisms of lactylation and its role in gynecological diseases: a comprehensive review. [PDF]
Zhang M, Li Y, Chen J, Xu Y, Zhao W.
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Inflammatory Crosstalk Between Type 2 Diabetes and Sarcopenia: Insights from In Silico Evaluation. [PDF]
Russo C +3 more
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Cross-species hepatic transcriptomics identify conserved immune-metabolic reprogramming in acute-on-chronic liver failure progression. [PDF]
Chen P +9 more
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NEAT1 is a therapeutic target for reversing T-cell exhaustion in bladder cancer. [PDF]
Li K +7 more
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