Results 31 to 40 of about 8,201 (155)

RORγt‐APCs: The New Masters of Oral Tolerance

Barrier Immunity, EarlyView.
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley   +1 more source

The Therapeutic Effectiveness of Full Spectrum Hemp Oil Using a Chronic Neuropathic Pain Model

Life, 2020
Background: Few models exist that can control for placebo and expectancy effects commonly observed in clinical trials measuring ‘Cannabis’ pharmacodynamics.
Jacob M. Vigil, Marena A. Montera, Nathan S. Pentkowski, Jegason P. Diviant, Joaquin Orozco, Anthony L. Ortiz, Lawrence J. Rael, Karin N. Westlund   +7 more
doaj   +1 more source

The influence of ultra‐processed foods on gut microbiome and inflammatory markers in schoolchildren from Northeastern Brazil

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective This study investigated the relationship between the consumption of ultra‐processed foods (UPF), dietary profile, and inflammation on the intestinal microbiome in children. Methods A cross‐sectional study was conducted using data from a community‐based controlled trial involving 82 children aged 7–11 years enrolled in public schools ...
Cristiane Cosmo Silva‐Luis, Paulo César Trindade da Costa, Vinicius José Baccin Martins, José Luiz de Brito Alves   +3 more
wiley   +1 more source

The Role of Artificial Intelligence in Modern Allergology: A Review of Applications in Diagnosis, Prediction, and Management

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial Intelligence is rapidly transforming allergology by enhancing diagnosis, risk prediction, automation, patient communication, education, and therapy development. Machine learning approaches, including convolutional neural networks, recurrent architectures, and transformer‐based models, enable analysis of complex datasets from ...
Sebastian Seurig, Stephan Traidl, Sonja Mathes   +2 more
wiley   +1 more source

Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food

Allergy, EarlyView.
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy, D. Schnoegl, V. Houghton, L. O'Mahony, A. F. Santos, E. F. Knol, A. Kuehn, T. Eiwegger   +7 more
wiley   +1 more source

Art v 1 and Amb a 4 Co‐Sensitization Identifies Italian Patients at Risk for Mugwort‐Celery‐Spice Syndrome

Allergy, EarlyView.
Three molecular profiles identified among Art v 1/Amb a 4‐sensitized patients: Art v 1 monosensitization, Amb a 4 monosensitization, and dual sensitization to both allergens. Art v 1 monosensitization was predominantly associated with allergic rhinitis, reflecting a classical airborne allergy pattern.
Enrico Scala, Gabriella Cusa, Valeria Villella, Damiano Abeni, Mauro Giani, Emma Cristina Guerra, Maria Locanto, Giorgia Meneguzzi, Lia Pirrotta, Donato Quaratino, Alessandra Zaffiro, Elisabetta Caprini, Maria Barrale, Ignazio Brusca, Valerio Pravettoni, Lorenzo Cecchi, Danilo Villalta, Martina Aumayr, Irene Mittermann, Christian Lupinek, Riccardo Asero   +20 more
wiley   +1 more source

Development of a mini pig model of peanut allergy

Frontiers in Allergy
IntroductionThe prevalence of peanut allergies is increasing, emphasizing the need for an animal model to enhance our understanding of peanut allergy pathogenesis and to advance diagnostic tools and therapeutic interventions.
Akhilesh Kumar Shakya, Brittany Backus, Lazar D. Nesovic, Malini Mallick, Olivia Banister, Carla M. Davis, Sara Anvari, Harvinder Singh Gill   +7 more
doaj   +1 more source

Diverging in Vivo Immune Response Patterns After Oral Food Challenge in Peanut Allergic Adults

Clinical &Experimental Allergy, EarlyView.
After the oral food challenge, peanut (PN)‐allergic adults were monitored over 4 weeks, which revealed diverging immune response patterns, with strong responders (SR) exhibiting heightened Ara h 2+ B cell expansion, PN sIgE induction and increasing PN‐specific Tconv. Weak responders (WR) had more activated PN‐specific Tregs.
Florent Fauchère, Aikaterina Alexiou, Veronika Höfer, Kirsten Beyer, Sabine Dölle‐Bierke, Andreas Thiel, Margitta Worm, Julian Braun   +7 more
wiley   +1 more source

Production of Recombinant Peanut Allergen Ara h 2 using Lactococcus lactis

Microbial Cell Factories, 2007
Background Natural allergen sources can supply large quantities of authentic allergen mixtures for use as immunotherapeutics. However, such extracts are complex, difficult to define, vary from batch to batch, which may lead to unpredictable efficacy and ...
Frøkiær Hanne, Madsen Søren M, Kato Kentaro, Poulsen Lars K, Glenting Jacob, Wendt Camilla, Sørensen Helle W   +6 more
doaj   +1 more source

Allergy to Peanuts in Atopic Dermatitis Patients 14 Year or Older and the Association with Food Hypersensitivity, Inhalant Allergens, Asthma Bronchiale and Rhinitis

Indian Journal of Dermatology, 2018
Background: In adult patients suffering from atopic dermatitis (AD), studies investigating the co-prevalence of AD and food allergy are still scarce, and exact data are not available. Aims and Objectives: To evaluate the occurrence of food allergy to peanuts in significant relation ...
Jarmila Celakovska, Josef Bukač, Karel Ettler, Jaroslava Vaneckova, Kvetuse Ettlerova   +4 more
openaire   +3 more sources